NOLC1 Antikörper

Produktnummer ABIN306630

Der Maus Monoklonal anti-NOLC1 Antikörper (Klon KAB40) (ABIN306630) detektiert spezifisch NOLC1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für NOLC1 Antikörper (ABIN306630)

Target: NOLC1 (Nucleolar and Coiled-Body Phosphoprotein 1 (NOLC1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NOLC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: KAB40

Produktdetails anti-NOLC1 Antikörper

Isotyp: IgG1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: -20 °C

Details zu NOLC1

Target: NOLC1 (Nucleolar and Coiled-Body Phosphoprotein 1 (NOLC1))

Andere Bezeichnung: p130

Hintergrund: The immunogen used was a GST fusion protein to the N terminus of p130. p130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107(collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors. This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130kDa. Synonyms: p130, Retinoblastoma-like protein 2, RBR-2, PRB2.

UniProt: Q08999

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling