Epstein-Barr Virus Nuclear Antigen-3A (EBNA-3A) Antikörper

Produktnummer ABIN306583

Dieser Schaf Polyklonal Antikörper detektiert spezifisch Epstein-Barr Virus Nuclear Antigen-3A in ELISA, IHC (fro), IHC (p), DB, ICC und WB. Es zeigt Reaktivität gegenüber Proben von Virus.

Kurzübersicht für Epstein-Barr Virus Nuclear Antigen-3A (EBNA-3A) Antikörper (ABIN306583)

Target: Epstein-Barr Virus Nuclear Antigen-3A (EBNA-3A)

Reaktivität: Virus

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Dot Blot (DB), Immunocytochemistry (ICC), Western Blotting (WB)

Produktdetails

Verwendungszweck: Sheep anti EBNA 3A

Produktmerkmale: EBNA-3A is a latent viral nuclear protein expressed in EBV transformed lymphoblastic cell lines. It is also found in some immunoblastic lymphomas in vivo. This viral nuclear protein is essential for EBV mediated transformation of B lymphocytes. The EBNA-3A functions as a transcriptional regulator though the target genes are currently unknown. Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop

Aufreinigung: Ammonium Sulfate Precipitation

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blotting at 0.25-1.00 μg/mL, Dot blotting, ELISA, Immunocytochemistry and Immunohistochemistry on frozen and paraffin embedded tissues. Optimal concentrations must be determined by titration.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Antigendetails

Target: Epstein-Barr Virus Nuclear Antigen-3A (EBNA-3A)

Andere Bezeichnung: EBNA 3A

Substanzklasse: Viral Protein

Hintergrund: EBNA3A, Epstein Barr Nuclear Antigen 3A

UniProt: Q69138