DC-SIGN/CD209 Antikörper (PE)
Kurzübersicht für DC-SIGN/CD209 Antikörper (PE) (ABIN306220)
Target
Alle DC-SIGN/CD209 (CD209) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Recognizes human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45kD C-type lectin that binds ICAM-3 which is also known as CD209. CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DCs in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DCs and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DCs. Clone MR-1 is reported to partially block the functional activity of DC-SIGN(2). XXX recommend the use of MCA2318EL for this purpose.
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Aufreinigung
- Protein G purified
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Immunogen
- Immature myeloid monocyte-derived dendritic cells (MDDCs).
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Isotyp
- IgG1
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Applikationshinweise
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Approved: Flo (1:1 - 1:10), IF
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request. -
Kommentare
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Target Species of Antibody: Human
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Distilled Water.
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Konzentration
- Lot specific
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Buffer
- Lyophilized, PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- DC-SIGN/CD209 (CD209) (CD209)
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Andere Bezeichnung
- CD209 / DC-SIGN
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Hintergrund
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Name/Gene ID: CD209
Synonyms: CD209, CD209 antigen, CD209 Molecule, CDSIGN, CLEC4L, DC-SIGN, HIV gpl20-binding protein, DC-SIGN1 -
Gen-ID
- 30835
Target
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