Integrin beta 3 Antikörper (PE)
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- Target Alle Integrin beta 3 (ITGB3) Antikörper anzeigen
- Integrin beta 3 (ITGB3)
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Reaktivität
- Maus, Ratte
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Wirt
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Hamster
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin beta 3 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Spezifität
- Recognizes the murine integrin beta 3 subunit (CD61), a 90kD type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3.1 is reported to partially inhibit the binding of CD61 to fibronectin. XXX recommend the use of MCA2299EL for this purpose.
- Aufreinigung
- Protein G purified
- Immunogen
- Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4.
- Isotyp
- IgG
- Top Product
- Discover our top product ITGB3 Primärantikörper
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- Applikationshinweise
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Approved: Flo (1:1 - 1:10), IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. - Kommentare
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Target Species of Antibody: Mouse
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Distilled Water.
- Konzentration
- Lot specific
- Buffer
- Lyophilized, PBS, pH 7.4, 0.09 % sodium azide, 1 % BSA.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 4°C. Do not freeze.
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- Target
- Integrin beta 3 (ITGB3)
- Andere Bezeichnung
- ITGB3 / Integrin beta 3 / CD61 (ITGB3 Produkte)
- Hintergrund
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Name/Gene ID: ITGB3
Family: Integrin
Synonyms: ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3 - Gen-ID
- 3690
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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