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Integrin beta 3 Antikörper (PE)

ITGB3 Reaktivität: Maus, Ratte FACS, IP Wirt: Hamster Monoclonal PE
Produktnummer ABIN306216
  • Target Alle Integrin beta 3 (ITGB3) Antikörper anzeigen
    Integrin beta 3 (ITGB3)
    Reaktivität
    • 184
    • 98
    • 67
    • 17
    • 15
    • 13
    • 12
    • 9
    • 8
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 120
    • 68
    • 15
    • 2
    • 2
    Hamster
    Klonalität
    • 115
    • 90
    Monoklonal
    Konjugat
    • 108
    • 16
    • 12
    • 10
    • 8
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Integrin beta 3 Antikörper ist konjugiert mit PE
    Applikation
    • 125
    • 94
    • 54
    • 46
    • 32
    • 29
    • 24
    • 20
    • 15
    • 13
    • 13
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Spezifität
    Recognizes the murine integrin beta 3 subunit (CD61), a 90kD type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3.1 is reported to partially inhibit the binding of CD61 to fibronectin. XXX recommend the use of MCA2299EL for this purpose.
    Aufreinigung
    Protein G purified
    Immunogen
    Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4.
    Isotyp
    IgG
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    Discover our top product ITGB3 Primärantikörper
  • Applikationshinweise
    Approved: Flo (1:1 - 1:10), IP

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
    Kommentare

    Target Species of Antibody: Mouse

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Distilled Water.
    Konzentration
    Lot specific
    Buffer
    Lyophilized, PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 4°C. Do not freeze.
  • Target
    Integrin beta 3 (ITGB3)
    Andere Bezeichnung
    ITGB3 / Integrin beta 3 / CD61 (ITGB3 Produkte)
    Hintergrund
    Name/Gene ID: ITGB3
    Family: Integrin

    Synonyms: ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3
    Gen-ID
    3690
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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