Integrin beta 3 Antikörper (PE)

Produktnummer ABIN306216

Dieses Anti-Integrin beta 3-Antikörper ist ein Hamster Monoklonal-Antikörper zur Detektion von Integrin beta 3 in FACS und IP. Geeignet für Maus und Ratte.

Kurzübersicht für Integrin beta 3 Antikörper (PE) (ABIN306216)

Target: Integrin beta 3 (ITGB3)

Reaktivität: Maus, Ratte

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser Integrin beta 3 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP)

Produktdetails anti-Integrin beta 3 Antikörper (PE)

Spezifität: Recognizes the murine integrin beta 3 subunit (CD61), a 90kD type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrand's factor (vWF), vitronectin and thrombospondin. Clone HM beta 3.1 is reported to partially inhibit the binding of CD61 to fibronectin. XXX recommend the use of MCA2299EL for this purpose.

Aufreinigung: Protein G purified

Immunogen: Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:1 - 1:10), IP

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled Water.

Konzentration: Lot specific

Buffer: Lyophilized, PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C. Do not freeze.

Details zu Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Andere Bezeichnung: ITGB3 / Integrin beta 3 / CD61

Hintergrund: Name/Gene ID: ITGB3
Family: Integrin

Synonyms: ITGB3, BDPLT2, CD61 antigen, GT, gp3A, CD61, GPIIIa, Integrin beta-3

Gen-ID: 3690

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex