D-Dimer (Fibrin Degradation Product) Antikörper

Produktnummer ABIN305042

Der Maus Monoklonal anti-D-Dimer (Fibrin Degradation Product) Antikörper wird verwendet zum Nachweis von D-Dimer (Fibrin Degradation Product) in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für D-Dimer (Fibrin Degradation Product) Antikörper (ABIN305042)

Target: D-Dimer (Fibrin Degradation Product)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: DD5

Produktdetails

Spezifität: Recognizes human D-dimer and shows low cross-reactivity with fibrinogen (D-monomer). D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease. Can be used as the detection antibody in ELISA for the detection of D-dimer in human plasma. Plasma samples must be diluted with 10 mM Tris-HCl buffer,  pH 7.5, containing 1 M NaCl (final concentration in sample >0.5 M) and 0.1 % Tween 20.

Aufreinigung: Affinity purified

Immunogen: Homogenized fibrin clot.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, WB

Usage: ELISA: This product may be used in an indirect ELISA or as a detection antibody in a sandwich ELISA together with clone DD1 (product code LS-C58035), for the detection of D-dimer in human plasma. Plasma samples must be diluted with 10 mM Tris-HCl buffer,  pH 7.5, containing 1 M NaCl (final concentration in sample >0.5 M) and 0.1 % Tween 20.WESTERN BLOT: Please note that non-reducing conditions are required for detection of the D-dimer.

Not recommended for: IHC-P

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Short term: -20°C
Long term: -20°C.

Antigendetails

Target: D-Dimer (Fibrin Degradation Product)

Andere Bezeichnung: Fibrin Degradation Product D-Dimer