RNH1 Antikörper (N-Term)

Produktnummer ABIN3044540

Der Kaninchen Polyklonal Anti-RNH1-Antikörper wurde für WB, IHC, FACS und ICC validiert. Er ist geeignet, RNH1 in Proben von Human, Maus, Ratte und Affe zu detektieren.

Kurzübersicht für RNH1 Antikörper (N-Term) (ABIN3044540)

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-RNH1 Antikörper

Bindungsspezifität: AA 2-37, N-Term

Verwendungszweck: Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband®

Sequenz: SLDIQSLDIQ CEELSDARWA ELLPLLQQCQ VVRLDD

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband® (ABIN3044540). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human RNH1, different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells
1. "Entrez Gene: RNH1 ribonuclease/angiogenin inhibitor 1". 2. Weremowicz S, Fox EA, Morton CC, Vallee BL (1991). "The placental ribonuclease inhibitor (RNH) gene is located on chromosome subband 11p15.5.". Genomics 8(4): 717-21. 3. Zneimer SM, Crawford D, Schneider NR, Beutler B (1991). "Mapping of the human ribonuclease inhibitor gene (RNH) to chromosome 11p15 by in situ hybridization.". Genomics 8 (1): 175-8.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu RNH1

Target: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Andere Bezeichnung: RNH1

Hintergrund:

Synonyms: Ribonuclease inhibitor,Placental ribonuclease inhibitor,Placental RNase inhibitor,Ribonuclease/angiogenin inhibitor 1,RAI,RNH1,PRI, RNH,

Tissue Specificity: Widely expressed, high expression found in skeletal muscle. .

Background: Ribonuclease inhibitor is an enzyme that in humans is encoded by the RNH1 gene. Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular Rnases. In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin. Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover, the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.

Molekulargewicht: 50 kDa

Gen-ID: 6050

UniProt: P13489