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Prokineticin 1 Antikörper (AA 20-105)

Prok1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3044536
  • Target Alle Prokineticin 1 (Prok1) Antikörper anzeigen
    Prokineticin 1 (Prok1)
    Bindungsspezifität
    • 13
    • 7
    • 7
    • 4
    • 2
    • 1
    • 1
    AA 20-105
    Reaktivität
    • 40
    • 6
    • 3
    Human
    Wirt
    • 31
    • 5
    • 4
    • 2
    Kaninchen
    Klonalität
    • 37
    • 5
    Polyklonal
    Konjugat
    • 19
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Prokineticin 1 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 16
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Verwendungszweck
    Anti-Prokineticin 1/PROK1 Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-Prokineticin 1/PROK1 Antibody Picoband® (ABIN3044536). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E. coli-derived human Prokineticin 1 recombinant protein (Position: A20-F105). Human Prokineticin 1 shares 88.4% and 91.9% amino acid (aa) sequence identity with mouse and rat Prokineticin 1, respectively.
    Isotyp
    IgG
    Top Product
    Discover our top product Prok1 Primärantikörper
  • Applikationshinweise
    ELISA, 0.1-0.5 μg/mL, -
    Western blot, 0.1-0.5 μg/mL, Human
    1. LeCouter, J., Kowalski, J., Foster, J., Hass, P., Zhang, Z., Dillard-Telm, L., Frantz, G., Rangell, L., DeGuzman, L., Keller, G.-A., Peale, F., Gurney, P., Hillan, K. J., Ferrara, N. Identification of an angiogenic mitogen selective for endocrine gland endothelium. Nature 412: 877-884, 2001. 2. Li, M., Bullock, C. M., Knauer, D. J., Ehlert, F. J., Zhou, Q. Y. Identification of two prokineticin cDNAs: recombinant proteins potently contract gastrointestinal smooth muscle. Molec. Pharm. 59: 692-698, 2001.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Yu, Chen, Jiang: "Administration of pigment epithelium-derived factor delivered by adeno-associated virus inhibits blood-retinal barrier breakdown in diabetic rats." in: Molecular vision, Vol. 16, pp. 2384-94, (2011) (PubMed).

  • Target
    Prokineticin 1 (Prok1)
    Andere Bezeichnung
    PROK1 (Prok1 Produkte)
    Hintergrund

    Synonyms: Prokineticin-1,Endocrine-gland-derived vascular endothelial growth factor,EG-VEGF,Mambakine,PROK1,UNQ600/PRO1186,

    Tissue Specificity: Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta. .

    Background: Prokineticin-1 is also known as EG-VEGF. The International Radiation Hybrid Mapping Consortium mapped the PROK1 gene to chromosome 1. The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.

    Molekulargewicht
    20 kDa
    Gen-ID
    84432
    UniProt
    P58294
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