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CXCL7 Antikörper (AA 55-128)

This anti-CXCL7 antibody (ABIN3044533) is a Rabbit Polyclonal antibody detecting CXCL7 in WB, IHC, ELISA. Suitable for Human.
Produktnummer ABIN3044533

Kurzübersicht für CXCL7 Antikörper (AA 55-128) (ABIN3044533)

Target

Alle CXCL7 (PPBP) Antikörper anzeigen
CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Reaktivität

  • 79
  • 18
  • 14
  • 3
  • 1
Human

Wirt

  • 74
  • 25
  • 5
  • 1
Kaninchen

Klonalität

  • 80
  • 25
Polyklonal

Konjugat

  • 53
  • 21
  • 16
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser CXCL7 Antikörper ist unkonjugiert

Applikation

  • 85
  • 47
  • 34
  • 23
  • 20
  • 8
  • 7
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Bindungsspezifität

    • 10
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 55-128

    Verwendungszweck

    Anti-NAP2/PPBP Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-NAP2/PPBP Antibody Picoband® (ABIN3044533). Tested in ELISA(Cap), IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E. coli-derived humn NAP2 recombinant protein (Position: S55-D128).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, -
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    ELISA(Cap) , 1-5 μg/mL, Human, -
    1. "Entrez Gene: PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)". 2. Hristov M, Zernecke A, Bidzhekov K, et al. (March 2007). "Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury".Circ. Res. 100 (4): 590-7. 3. Majumdar S, Gonder D, Koutsis B, Poncz M (1991). "Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4". J Biol Chem 266 (9): 5785-9.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

    Andere Bezeichnung

    PPBP

    Hintergrund

    Synonyms: Platelet basic protein;PBP;C-X-C motif chemokine 7;Leukocyte-derived growth factor;LDGF;Macrophage-derived growth factor;MDGF;Small-inducible cytokine B7;Connective tissue-activating peptide III;CTAP-III;LA-PF4;Low-affinity platelet factor IV;TC-2;Connective tissue-activating peptide III (1-81);CTAP-III (1-81);Beta-thromboglobulin;Beta-TG;Neutrophil-activating peptide 2 (74);NAP-2 (74);Neutrophil-activating peptide 2 (73);NAP-2 (73);Neutrophil-activating peptide 2;NAP-2;TC-1;Neutrophil-activating peptide 2 (1-66);NAP-2 (1-66);Neutrophil-activating peptide 2 (1-63);NAP-2 (1-63);PPBP;CTAP3, CXCL7, SCYB7, TGB1, THBGB1;

    Tissue Specificity: Restricted to the nervous system. Highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. .

    Background: Chemokine (C-X-C motif) ligand 7  (CXCL7), also known as NAP2 or Pro-Platelet basic protein  (PPBP), is a human gene. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Furthermore, the protein is an antimicrobial protein with bactericidal and antifungal activity.

    Molekulargewicht

    19 kDa

    Gen-ID

    5473

    UniProt

    P02775
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