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SCG3 Antikörper (C-Term)

SCG3 Reaktivität: Human, Maus, Ratte WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3044496
  • Target Alle SCG3 Antikörper anzeigen
    SCG3 (Secretogranin III (SCG3))
    Bindungsspezifität
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 438-450, C-Term
    Reaktivität
    • 49
    • 21
    • 14
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 48
    • 1
    Kaninchen
    Klonalität
    • 48
    • 1
    Polyklonal
    Konjugat
    • 29
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SCG3 Antikörper ist unkonjugiert
    Applikation
    • 31
    • 16
    • 14
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Verwendungszweck
    Anti-Secretogranin 3/SCG3 Antibody Picoband®
    Sequenz
    DFINKQADAY VEK
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-Secretogranin 3/SCG3 Antibody (ABIN3044496). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human Secretogranin 3, different from the related mouse and rat sequences by one amino acid.
    Isotyp
    IgG
    Top Product
    Discover our top product SCG3 Primärantikörper
  • Applikationshinweise
    Immunocytochemistry , 0.5-1 μg/mL, Human, -
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, Rat, Mouse
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    1. Related Articles, LinksTanabe A, Yanagiya T, Iida A, Saito S, Sekine A, Takahashi A, Nakamura T, Tsunoda T, Kamohara S, Nakata Y, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Funahashi T, Miyazaki S, Tokunaga K, Hamaguchi K, Shimada T, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y, Hotta K.Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.J Clin Endocrinol Metab. 2007 Mar,92(3):1145-54. Epub 2007 Jan 2.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    SCG3 (Secretogranin III (SCG3))
    Andere Bezeichnung
    SCG3 (SCG3 Produkte)
    Hintergrund

    Synonyms: Secretogranin-3,Secretogranin III,SgIII,SCG3,UNQ2502/PRO5990,

    Tissue Specificity: Expressed in brain, heart, kidney, liver and skeletal muscle. .

    Background: SCG3 (secretogranin III) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Genetic variations in the SCG3 gene may influence the risk of obesity through possible regulation of hypothalamic neuropeptide secretion. SCG3 was the only gene within a haplotype block that contained rs3764220. SCG3 mRNA and immunoreactivity were detected in the paraventricular nucleus, lateral hypothalamic area, and arcuate nucleus, and the protein coexisted with orexin, melanin-concentrating hormone, neuropeptide Y, and proopiomelanocortin. SCG3 formed a granule-like structure together with these neuropeptides.

    Sequence Similarities: Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

    Molekulargewicht
    62-65 kDa
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