Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

SCG3 Antikörper (C-Term)

Dieses Anti-SCG3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SCG3 in WB, IHC und ICC. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN3044496

Kurzübersicht für SCG3 Antikörper (C-Term) (ABIN3044496)

Target

Alle SCG3 Antikörper anzeigen
SCG3 (Secretogranin III (SCG3))

Reaktivität

  • 51
  • 21
  • 15
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 49
  • 2
Kaninchen

Klonalität

  • 49
  • 2
Polyklonal

Konjugat

  • 31
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SCG3 Antikörper ist unkonjugiert

Applikation

  • 33
  • 16
  • 15
  • 8
  • 7
  • 6
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 438-450, C-Term

    Verwendungszweck

    Anti-Secretogranin 3/SCG3 Antibody Picoband®

    Sequenz

    DFINKQADAY VEK

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Secretogranin 3/SCG3 Antibody (ABIN3044496). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human Secretogranin 3, different from the related mouse and rat sequences by one amino acid.

    Isotyp

    IgG
  • Applikationshinweise

    Immunocytochemistry , 0.5-1 μg/mL, Human, -
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, Rat, Mouse
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    1. Related Articles, LinksTanabe A, Yanagiya T, Iida A, Saito S, Sekine A, Takahashi A, Nakamura T, Tsunoda T, Kamohara S, Nakata Y, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Funahashi T, Miyazaki S, Tokunaga K, Hamaguchi K, Shimada T, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y, Hotta K.Functional single-nucleotide polymorphisms in the secretogranin III (SCG3) gene that form secretory granules with appetite-related neuropeptides are associated with obesity.J Clin Endocrinol Metab. 2007 Mar,92(3):1145-54. Epub 2007 Jan 2.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    SCG3 (Secretogranin III (SCG3))

    Andere Bezeichnung

    SCG3

    Hintergrund

    Synonyms: Secretogranin-3,Secretogranin III,SgIII,SCG3,UNQ2502/PRO5990,

    Tissue Specificity: Expressed in brain, heart, kidney, liver and skeletal muscle. .

    Background: SCG3 (secretogranin III) is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Genetic variations in the SCG3 gene may influence the risk of obesity through possible regulation of hypothalamic neuropeptide secretion. SCG3 was the only gene within a haplotype block that contained rs3764220. SCG3 mRNA and immunoreactivity were detected in the paraventricular nucleus, lateral hypothalamic area, and arcuate nucleus, and the protein coexisted with orexin, melanin-concentrating hormone, neuropeptide Y, and proopiomelanocortin. SCG3 formed a granule-like structure together with these neuropeptides.

    Sequence Similarities: Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

    Molekulargewicht

    62-65 kDa
Sie sind hier:
Chat with us!