IFITM1 Antikörper (N-Term)
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- Target Alle IFITM1 Antikörper anzeigen
- IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
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Bindungsspezifität
- AA 1-17, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IFITM1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Interferon-induced transmembrane protein 1(IFITM1) detection. Tested with WB, IHC-P, IHC-F in Human.
- Sequenz
- MHKEEHEVAV LGPPPST
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Interferon-induced transmembrane protein 1(IFITM1) detection. Tested with WB, IHC-P, IHC-F in Human.
Gene Name: interferon induced transmembrane protein 1
Protein Name: Interferon-induced transmembrane protein 1 - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human IFITM1(1-17aa MHKEEHEVAVLGPPPST).
- Isotyp
- IgG
- Top Product
- Discover our top product IFITM1 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression." in: Oncology reports, Vol. 23, Issue 6, pp. 1569-76, (2010) (PubMed).
: "Binding of IFITM1 enhances the inhibiting effect of caveolin-1 on ERK activation." in: Acta biochimica et biophysica Sinica, Vol. 41, Issue 6, pp. 488-94, (2009) (PubMed).
: "IFITM1 plays an essential role in the antiproliferative action of interferon-gamma." in: Oncogene, Vol. 26, Issue 4, pp. 594-603, (2007) (PubMed).
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Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression." in: Oncology reports, Vol. 23, Issue 6, pp. 1569-76, (2010) (PubMed).
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- Target
- IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))
- Andere Bezeichnung
- IFITM1 (IFITM1 Produkte)
- Synonyme
- 9-27 antikoerper, CD225 antikoerper, DSPA2a antikoerper, IFI17 antikoerper, LEU13 antikoerper, 1110036C17Rik antikoerper, Mil-2 antikoerper, Mil2 antikoerper, interferon induced transmembrane protein 1 antikoerper, interferon induced transmembrane protein 1 (9-27) antikoerper, Ifitm1 antikoerper, IFITM1 antikoerper
- Hintergrund
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Interferon-induced Transmembrane Protein 1(IFITM1), also called Interferon-induced Protein 17(IFI17). IFITM1 activity is required for primordial germ cells(PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins(Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17- kDa proteins to inhibit cell growth.
Synonyms: 9-27 antibody|CD 225 antibody|CD 225 antigen antibody|CD225 antibody|CD225 antigen antibody|Dispanin subfamily A member 2a antibody|DSPA2a antibody|IFI 17 antibody|IFI17 antibody|IFITM1 antibody|IFM1_HUMAN antibody|Interferon induced protein 17 antibody|interferon induced transmembrane protein 1(9-27) antibody|Interferon induced transmembrane protein 1 antibody|Interferon inducible protein 9-27 antibody|Interferon-induced protein 17 antibody|Interferon-induced transmembrane protein 1 antibody|Interferon-inducible protein 9-27 antibody|Leu 13 antibody|Leu 13 antigen antibody|Leu-13 antigen antibody|LEU13 antibody - UniProt
- P13164
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