Myoglobin Antikörper (C-Term)

Produktnummer ABIN3044306

Der Kaninchen Polyklonal Anti-Myoglobin-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Myoglobin in Proben von Human, Ratte und Maus zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für Myoglobin Antikörper (C-Term) (ABIN3044306)

Target: Myoglobin (MB)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myoglobin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Myoglobin Antikörper

Bindungsspezifität: AA 138-154, C-Term

Verwendungszweck: Anti-Myoglobin/MB Antibody Picoband®

Sequenz: LFRNDIAAKY KELGFQG

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Rabbit IgG polyclonal antibody for Myoglobin(MB) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: myoglobin
Protein Name: myoglobin

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Myoglobin, identical to the related rat sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
1. Boyer, S. H., Fainer, D. C., Naughton, M. A. Myoglobin inherited structural variation in man. Science 140: 1228-1231, 1963. 2. Boulton, F. E., Huntsman, R. G., Lorkin, P. A., Lehmann, H. Abnormal human myoglobin: 53(D4) glutamic acid lysine. Nature 223: 832-833, 1969. 3. Jeffreys, A. J., Wilson, V., Blanchetot, A., Weller, P., Geurts van Kessel, A., Spurr, N., Solomon, E., Goodfellow, P. The human myoglobin gene: a third dispersed globin locus in the human genome. Nucleic Acids Res. 12: 3235-3243, 1984.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Myoglobin Antikörper (ABIN3044306)

Xu, He, Zhang, Fan, Zhao, Xu, Nie, Li, Huang, Lu, Xu: "Synthesis and in vitro evaluation of a hyaluronic acid-quantum dots-melphalan conjugate." in: Carbohydrate polymers, Vol. 121, pp. 132-9, (2015) (PubMed).

Peng, Yanjiao, Ai-guo, Pengtao, Jianhua, Ju, Hongsheng, Xichen: "A fine balance between CCNL1 and TIMP1 contributes to the development of breast cancer cells." in: Biochemical and biophysical research communications, Vol. 409, Issue 2, pp. 344-9, (2011) (PubMed).

Details zu Myoglobin

Target: Myoglobin (MB)

Andere Bezeichnung: Myoglobin

Hintergrund:

Synonyms: Myoglobin,Mb,

Background: Myoglobin (MB) also known as PVALB, is a single-chain globular protein of 153 or 154 amino acids, containing a heme (iron-containing porphyrin) prosthetic group in the center around which the remaining apoprotein folds. It is a member of the globin superfamily and is expressed in skeletal and cardiac muscles. This gene is mapped to chromosome 22q11-q13. Myoglobin is released from damaged muscle tissue (rhabdomyolysis), which has very high concentrations of myoglobin. The released myoglobin is filtered by the kidneys but is toxic to the renal tubular epithelium and so may cause acute renal failure.

Molekulargewicht: 17 kDa

UniProt: P04247

Pathways: Brown Fat Cell Differentiation