Tenascin R Antikörper (N-Term)

Produktnummer ABIN3044266

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Tenascin R in IHC und WB. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für Tenascin R Antikörper (N-Term) (ABIN3044266)

Target: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tenascin R Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-Tenascin R Antikörper

Bindungsspezifität: AA 104-117, N-Term

Verwendungszweck: Anti-Tenascin-R TNR Antibody Picoband®

Sequenz: QTSDHESQVT FTHK

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Tenascin-R TNR Antibody (ABIN3044266). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse TNR, identical to the related rat sequence, and different from the related human sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Leprini, A., Gherzi, R., Siri, A., Querze, G., Viti, F., Zardi, L.The human tenascin-R gene.J. Biol. Chem. 271: 31251-31254, 1996. 2. Saghatelyan, A., de Chevigny, A., Schachner, M., Lledo, P.-M.Tenascin-R mediates activity-dependent recruitment of neuroblasts in the adult mouse forebrain.Nature Neurosci. 7: 347-356, 2004. 3. Williams, H., Schachner, M., Wang, B., Kenwrick, S.Radiation hybrid mapping of the genes for tenascin-R (TNR), phosducin (PDC), Laminin C1 (LAMC1), and TAX in 1q25-q32.Genomics 46: 165-166, 1997.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Tenascin R

Target: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Andere Bezeichnung: TNR

Hintergrund:

Synonyms: Tenascin-R,TN-R,Janusin,Restrictin,TNR,

Tissue Specificity: Brain specific. .

Background: Tenascin-R is a protein that in humans is encoded by the TNR gene. Tenascin-R (TNR) is an extracellular matrix protein expressed primarily in the central nervous system. It is a member of the tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion), TNX (TNXB), and TNR. The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues. TNR has been detected predominantly in the central nervous system and is localized around motor neurons and on motor axons in the spinal cord, cerebellum, hippocampus, and olfactory bulb. It is suggested that tenascin-R has a role in initiating the detachment of neuroblasts from tangential chains and in initiating radial migration of the cells.

Sequence Similarities: Belongs to the tenascin family.

Molekulargewicht: 150 kDa

UniProt: Q92752

Pathways: Regulation of Cell Size