ALDH1A1 Antikörper (Middle Region)

Produktnummer ABIN3044255

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-ALDH1A1 Antikörper wird verwendet zum Nachweis von ALDH1A1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, FACS, IF und ICC.

Kurzübersicht für ALDH1A1 Antikörper (Middle Region) (ABIN3044255)

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALDH1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-ALDH1A1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-Retinal dehydrogenase 1 ALDH1A1 Antibody

Sequenz: DLDNAVEFAH HGVFYHQGQC C

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: different from the related rat,mouse sequences by one amino acid.

Produktmerkmale: Anti-Retinal dehydrogenase 1 ALDH1A1 Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ALDH1A1, different from the related rat and mouse sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat, Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-ALDH1A1 Antikörper (ABIN3044255)

Shao, Fan, Ma, Wu: "Breast cancer stem cells expressing different stem cell markers exhibit distinct biological characteristics." in: Molecular medicine reports, Vol. 14, Issue 6, pp. 4991-4998, (2017) (PubMed).

Details zu ALDH1A1

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Andere Bezeichnung: ALDH1A1

Hintergrund:

Background: ALDH1A1 (Aldehyde dehydrogenase 1 family, member A1), also called ALDH1, RALDH1 or ALDH, LIVER CYTOSOLIC, is an enzyme that in humans is encoded by the ALDH1A1 gene. And this protein belongs to the aldehyde dehydrogenases family of proteins. The ALDH1A1 gene is mapped on 9q21.13. ALDH1A1 also belongs to the group of corneal crystallins that help maintain the transparency of the cornea.ALDH1A1 is associated with a low Km for NAD, a high Km for acetaldehyde, and is strongly inactivated by disulfiram. The ALDH1 gene is about 53 kb long and is divided into 13 exons. Retinaldehyde is generated by ADH1 from retinol, and its concentration is determined in large part by its subsequent catabolism by RALDH1 to retinoic acid.

Gene Full Name: aldehyde dehydrogenase 1 family member A1

Sequence Similarities: Belongs to the aldehyde dehydrogenase family.

Molekulargewicht: 65 kDa

Gen-ID: 216

UniProt: P00352

Pathways: Dopaminergic Neurogenesis