Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

HSPB2 Antikörper (Middle Region)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HSPB2 in WB, IHC und ICC. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN3044185

Kurzübersicht für HSPB2 Antikörper (Middle Region) (ABIN3044185)

Target

Alle HSPB2 Antikörper anzeigen
HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))

Reaktivität

  • 36
  • 28
  • 28
  • 6
  • 5
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 52
  • 5
Kaninchen

Klonalität

  • 52
  • 5
Polyklonal

Konjugat

  • 32
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HSPB2 Antikörper ist unkonjugiert

Applikation

  • 43
  • 20
  • 15
  • 14
  • 13
  • 13
  • 8
  • 8
  • 6
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 15
    • 12
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 102-118, Middle Region

    Verwendungszweck

    Anti-Heat shock protein beta-2 HSPB2 Antibody Picoband®

    Sequenz

    RHPQRLDRHG FVSREFC

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Heat shock protein beta-2 HSPB2 Antibody (ABIN3044185). Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence in the middle region of human HSPB2, identical to the related rat and mouse sequences.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Rat, Human, Mouse
    Immunocytochemistry , 0.5-1 μg/mL, Human, Mouse, Rat
    1. Iwaki, A., Nagano, T., Nakagawa, M., Iwaki, T., Fukumaki, Y. Identification and characterization of the gene encoding a new member of the alpha-crystallin/Small hsp family, closely linked to the alpha-B-crystallin gene in a head-to-head manner. Genomics 45: 386-394, 1997.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(F) and ICC.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    HSPB2 (Heat Shock 27kDa Protein 2 (HSPB2))

    Andere Bezeichnung

    HSPB2

    Hintergrund

    Synonyms: Heat shock protein beta-2,HspB2,DMPK-binding protein,MKBP,HSPB2,

    Tissue Specificity: Expressed preferentially in skeletal muscle and heart but not in the lens.

    Background: Alpha-B-crystallin is a member of the alpha-crystallin/small heat-shock protein (HSP) family and under various neuropathologic conditions accumulates in reactive astrocytes and degenerating neurons. In the 5-prime flanking region of the CRYAB gene on 11q22-q23, where a constitutive DNaseI hypersensitive site is located, Iwaki et al. (1997) identified a gene transcribed in the opposite ion. Analysis of its mRNA structure by RT-PCR and 5-prime/3-prime RACE revealed that this gene is composed of 2 exons and encodes a new member of the alpha-crystallin/hsp family. They termed the gene HSPB2. Iwaki et al. (1997) also determined the complete genomic structure of the rat homolog of HSPB2. Southern blot analysis demonstrated that HSPB2is expressed preferentially in skeletal muscle and heart but not in the lens, while the neighboring CRYAB gene is highly expressed in all 3 tissues. The 2 related genes are arranged in a head-to-head manner with an intergenic sequence of less than 1 kb, raising a possibility of shared regulatory elements for their expression.

    Sequence Similarities: Belongs to the small heat shock protein (HSP20) family.

    Molekulargewicht

    23 kDa

    UniProt

    Q16082
Sie sind hier:
Chat with us!