KLF3 Antikörper (N-Term)

Produktnummer ABIN3044105

Produktdetails anti-KLF3 Antikörper

Target: KLF3 (Kruppel-Like Factor 3 (Basic) (KLF3))

Bindungsspezifität: AA 20-34, N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Krueppel-like factor 3(KLF3) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: SYPSNYMESM KPNKY

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Krueppel-like factor 3(KLF3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: Kruppel-like factor 3(basic)
Protein Name: Krueppel-like factor 3

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human KLF3(20-34aa SYPSNYMESMKPNKY), different from the related rat sequence by one amino acid, and from the related mouse sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for KLF3 is approximately 2.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu KLF3

Target: KLF3 (Kruppel-Like Factor 3 (Basic) (KLF3))

Andere Bezeichnung: KLF3 (KLF3 Produkte)

Synonyme: BKLF antikoerper, 9930027G08Rik antikoerper, AL024007 antikoerper, Bklf antikoerper, Tef-2 antikoerper, klf12 antikoerper, Kruppel like factor 3 antikoerper, Kruppel-like factor 3 (basic) antikoerper, KLF3 antikoerper, Klf3 antikoerper, klf3 antikoerper

Hintergrund: KLF3(Krueppel-like factor 3) is a protein that in humans is encoded by the KLF3 gene. It is also known as BKLF(Basic kruppel-like factor). KLF3 is a member of the Krüppel-like factors family of transcription factors. KLF3 primarily represses transcription through the transcriptional corepressor C-terminal binding protein(CtBP). Suske et al.(2005) stated that the human KLF3 gene maps to chromosome 4p14, and the mouse Klf3 gene maps to chromosome 5C3.3. Suske et al.(2005) stated that the human and mouse KLF3 proteins contain 345 and 344 amino acids, respectively. Both have a characteristic zinc finger domain, but lack the N-terminal buttonhead box found in related SP transcription factors. The repression mediated through KLF3 is also partially dependent on the sumoylation of its K10 and K197. Within KLF3's C-terminal, which is highly conserved throughout the KLF family, resides three C2H2 zinc fingers that preferentially bind the site NRG GNG NGR.

Synonyms: Basic krueppel-like factor antibody|Basic Kruppel like factor antibody|BKLF3 antibody|CACCC box binding protein BKLF antibody|CACCC-box-binding protein BKLF antibody|Klf3 antibody|KLF3_HUMAN antibody|Krueppel-like factor 3 antibody|Kruppel like factor 3(basic) antibody|MGC48279 antibody|TEF-2 antibody|TEF2 antibody|Transcript ch138 antibody|Zinc finger protein 741 antibody|ZNF741 antibody

UniProt: P57682