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HYAL3 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HYAL3 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human und Maus.
Produktnummer ABIN3044086

Kurzübersicht für HYAL3 Antikörper (C-Term) (ABIN3044086)

Target

Alle HYAL3 Antikörper anzeigen
HYAL3 (Hyaluronidase-3 (HYAL3))

Reaktivität

  • 36
  • 19
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 32
  • 4
Kaninchen

Klonalität

  • 35
  • 1
Polyklonal

Konjugat

  • 16
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HYAL3 Antikörper ist unkonjugiert

Applikation

  • 27
  • 13
  • 13
  • 10
  • 6
  • 5
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 6
    • 4
    • 3
    • 1
    AA 357-371, C-Term

    Verwendungszweck

    Anti-Hyaluronidase-3 HYAL3 Antibody Picoband®

    Sequenz

    SHQRCHGHGR CARRD

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Hyaluronidase-3 HYAL3 Antibody (ABIN3044086). Tested in IHC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human HYAL3, different from the related rat sequence by three amino acids, and different from the related mouse sequence by one amino acid.

    Isotyp

    IgG
  • Applikationshinweise

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse
    Western blot, 0.1-0.5 μg/mL, Human, Mouse
    1. Csoka, A. B., Scherer, S. W., Stern, R. Expression analysis of six paralogous human hyaluronidase genes clustered on chromosomes 3p21 and 7q31.Genomics 60: 356-361, 1999.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    HYAL3 (Hyaluronidase-3 (HYAL3))

    Andere Bezeichnung

    HYAL3

    Hintergrund

    Synonyms: Hyaluronidase-3;Hyal-3;3.2.1.35;Hyaluronoglucosaminidase-3;Lung carcinoma protein 3;LuCa-3;HYAL3;LUCA3;

    Tissue Specificity: Bone marrow, testis and kidney. Isoform 4 is detected in all bladder tumor and prostate tumor cells. .

    Background: HYAL3 (hyaluronoglucosaminidase 3) is an enzyme that in humans is encoded by the HYAL3 gene, also known as LUCA3, Hyaluronidase-3, Lung carcinoma protein 3, LUCA-3, LUCA14, Minna14. By Northern blot analysis, expression of a 2.1-kb HYAL3 transcript that was strongest in testis and bone marrow, but relatively weak in other organs. HYAL3 encodes a predicted 417-amino acid protein. This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression.

    Sequence Similarities: Belongs to the glycosyl hydrolase 56 family.

    Molekulargewicht

    93 kDa

    UniProt

    O43820

    Pathways

    Glycosaminoglycan Metabolic Process
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