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ADAM19 Antikörper (N-Term)

Adam19 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3044069
  • Target Alle ADAM19 (Adam19) Antikörper anzeigen
    ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))
    Bindungsspezifität
    • 14
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 286-298, N-Term
    Reaktivität
    • 39
    • 11
    • 9
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 37
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 39
    • 1
    Polyklonal
    Konjugat
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ADAM19 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 12
    • 12
    • 10
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB)
    Verwendungszweck
    Anti-ADAM19 Antibody Picoband®
    Sequenz
    RRKLLAQKYH DNA
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-ADAM19 Antibody (ABIN3044069). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human ADAM19, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product Adam19 Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL, Human
    1. Hirohata, S., Seldin, M. F., Apte, S. S. Chromosomal assignment of two ADAM genes, TACE (ADAM17) and MLTNB (ADAM19), to human chromosomes 2 and 5, respectively, and of Mltnb to mouse chromosome 11. Genomics 54: 178-179, 1998. 2. Inoue, D., Reid, M., Lum, L., Kratzschmar, J., Weskamp, G., Myung, Y. M., Baron, R., Blobel, C. P. Cloning and initial characterization of mouse meltrin beta and analysis of the expression of four metalloprotease-disintegrins in bone cells. J. Biol. Chem. 273: 4180-4187, 1998.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ADAM19 (Adam19) (ADAM Metallopeptidase Domain 19 (Adam19))
    Andere Bezeichnung
    ADAM19 (Adam19 Produkte)
    Hintergrund

    Synonyms: Disintegrin and metalloproteinase domain-containing protein 19,ADAM 19,3.4.24.-,Meltrin-beta,Metalloprotease and disintegrin dendritic antigen marker,MADDAM,ADAM19,MLTNB,FKSG34,

    Tissue Specificity: Expressed in many normal organ tissues and several cancer cell lines.

    Background: ADAM19 (A Disintegrin and Metalloproteinase Domain 19), also known as MLTNB, is a human gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. Hirohata et al. (1998) used radiation hybrids to map ADAM19 to mouse chromosome 11 and to human chromosome 5q32-q33.

    Sequence Similarities: Contains 1 disintegrin domain.

    Molekulargewicht
    105 kDa
    UniProt
    Q9H013
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