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TRAM1 Antikörper (C-Term)

Dieses Anti-TRAM1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TRAM1 in WB, IHC, ICC und IHC (fro). Geeignet für Human, Maus und Ratte.
Produktnummer ABIN3044049

Kurzübersicht für TRAM1 Antikörper (C-Term) (ABIN3044049)

Target

Alle TRAM1 Antikörper anzeigen
TRAM1 (Translocation Associated Membrane Protein 1 (TRAM1))

Reaktivität

  • 37
  • 4
  • 3
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 34
  • 3
Kaninchen

Klonalität

  • 36
  • 1
Polyklonal

Konjugat

  • 18
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TRAM1 Antikörper ist unkonjugiert

Applikation

  • 37
  • 13
  • 13
  • 12
  • 7
  • 6
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 15
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 314-331, C-Term

    Verwendungszweck

    Anti-TRAM1 Antibody Picoband®

    Sequenz

    KFINFQLRRW REHSAFQA

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-TRAM1 Antibody (ABIN3044049). Tested in IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human TRAM1, identical to the related rat and mouse sequences.

    Isotyp

    IgG
  • Applikationshinweise

    Immunocytochemistry , 0.5-1 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Rat, Human, Mouse
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    1. Gorlich, D., Hartmann, E., Prehn, S., Rapoport, T. A. A protein of the endoplasmic reticulum involved early in polypeptide translocation. Nature 357: 47-52, 1992.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F)and ICC.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    TRAM1 (Translocation Associated Membrane Protein 1 (TRAM1))

    Andere Bezeichnung

    TRAM1

    Hintergrund

    Synonyms: Translocating chain-associated membrane protein 1,TRAM1,TRAM,

    Background: TRAM1 (Translocation-Associating Membrane Protein 1), By crosslinking and reconstitution of canine proteoliposomes, followed by microsequencing and PCR screening of canine kidney and HeLa cell cDNA libraries, Gorlich et al. (1992) isolated cDNAs encoding TRAM (translocating chain-associating membrane protein). The International Radiation Hybrid Mapping Consortium mapped the TRAM gene to chromosome 8. Sequence analysis predicted that human TRAM is a 374-amino acid, 8-pass transmembrane protein that shares 95 % amino acid identity with the canine protein. Functional analysis indicated that TRAM influences glycosylation and is stimulatory or required for the translocation of secretory proteins.

    Sequence Similarities: Belongs to the TRAM family.

    Molekulargewicht

    56 kDa

    UniProt

    Q15629
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