ADRA2A Antikörper (Middle Region)

Produktnummer ABIN3044006

Produktdetails anti-ADRA2A Antikörper

Target: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Bindungsspezifität: AA 213-228, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADRA2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Alpha-2A adrenergic receptor(ADRA2A) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: ILVYVRIYQI AKRRTR

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Alpha-2A adrenergic receptor(ADRA2A) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: adrenoceptor alpha 2A
Protein Name: Alpha-2A adrenergic receptor

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human alpha 2a Adrenergic Receptor(213-228aa ILVYVRIYQIAKRRTR), identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ADRA2A

Target: ADRA2A (Alpha-2A Adrenergic Receptor (ADRA2A))

Andere Bezeichnung: ADRA2A (ADRA2A Produkte)

Synonyme: ADRA2A antikoerper, AW122659 antikoerper, Adra-2 antikoerper, Adra-2a antikoerper, alpha(2A)AR antikoerper, alpha2-C10 antikoerper, alpha2A antikoerper, alpha2A-AR antikoerper, ADRA2 antikoerper, ADRA2R antikoerper, ADRAR antikoerper, ALPHA2AAR antikoerper, ZNF32 antikoerper, CA2-47 antikoerper, RATRG20 antikoerper, RG20 antikoerper, PORA2AR antikoerper, adrenoceptor alpha 2A antikoerper, alpha-2A adrenergic receptor-like antikoerper, adrenergic receptor, alpha 2a antikoerper, adra2a antikoerper, ADRA2A antikoerper, LOC100414445 antikoerper, Adra2a antikoerper

Hintergrund: The alpha-2A adrenergic receptor, also known as ADRA2A denotes the human gene encoding it. This gene is mapped to 10q25.2. Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons, the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.

Synonyms: ADA2A_HUMAN antibody|ADRA2 antibody|ADRA2A antibody|ADRA2R antibody|ADRAR antibody|Adrenergic alpha 2A receptor antibody|Alpha 2 adrenergic receptor subtype C10 antibody|Alpha 2A adrenergic receptor antibody|Alpha 2AAR subtype C10 antibody|Alpha-2 adrenergic receptor subtype C10 antibody|alpha-2-adrenergic receptor, platelet type antibody|Alpha-2A adrenergic receptor antibody|Alpha-2A adrenoceptor antibody|Alpha-2A adrenoreceptor antibody|Alpha-2AAR antibody|ALPHA2AAR antibody|OTTHUMP00000058849 antibody|ZNF32 antibody

UniProt: P08913

Pathways: EGFR Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Negative Regulation of Transporter Activity