EGR1 Antikörper (N-Term)

Produktnummer ABIN3043997

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-EGR1 Antikörper wird verwendet zum Nachweis von EGR1 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für EGR1 Antikörper (N-Term) (ABIN3043997)

Target: EGR1 (Early Growth Response 1 (EGR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EGR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EGR1 Antikörper

Bindungsspezifität: AA 23-43, N-Term

Verwendungszweck: Anti-Egr1 Antibody

Sequenz: FPHSPTMDNY PKLEEMMLLS N

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Egr1 Antibody (ABIN3043997). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Egr1, identical to the related rat and mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-EGR1 Antikörper (ABIN3043997)

Lin, Fang, Cai, Huang, Zhang, Lu, Zhang, Wei: "ERK/Egr-1 signaling pathway is involved in CysLT2 receptor-mediated IL-8 production in HEK293 cells." in: European journal of cell biology, Vol. 93, Issue 7, pp. 278-88, (2014) (PubMed).

Details zu EGR1

Target: EGR1 (Early Growth Response 1 (EGR1))

Andere Bezeichnung: EGR1

Hintergrund:

Synonyms: Early growth response protein 1,EGR-1,AT225,Nerve growth factor-induced protein A,NGFI-A,Transcription factor ETR103,Transcription factor Zif268,Zinc finger protein 225,Zinc finger protein Krox-24,EGR1,KROX24, ZNF225,

Tissue Specificity: In eosinophils as well as trace amounts in neutrophils and monocytes.

Background: Earlu growth response protein 1, also known as ZIF268 or NGFIA, is a protein that in humans is encoded by the EGR1 gene. The protein encoded by this gene belongs to the EGR family of C2H2-type zinc-finger proteins. This gene is mapped to 5q31.2. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppresor gene. It has a distinct pattern of expression in the brain, and its induction has been shown to be associated with neuronal activity. Several studies suggest it has a role in neuronal plasticity.

Sequence Similarities: Belongs to the EGR C2H2-type zinc-finger protein family.

Molekulargewicht: 58 kDa

UniProt: P18146

Pathways: Regulation of Carbohydrate Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity