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RAB13 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-RAB13-Antikörper wurde für WB, FACS, IF und ICC validiert. Er ist geeignet, RAB13 in Proben von Human zu detektieren.
Produktnummer ABIN3043916

Kurzübersicht für RAB13 Antikörper (C-Term) (ABIN3043916)

Target

Alle RAB13 Antikörper anzeigen
RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Reaktivität

  • 16
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 9
  • 7
Kaninchen

Klonalität

  • 9
  • 7
Polyklonal

Konjugat

  • 16
Dieser RAB13 Antikörper ist unkonjugiert

Applikation

  • 13
  • 8
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-150, C-Term

    Verwendungszweck

    Anti-RAB13 Antibody Picoband®

    Sequenz

    NKCDMEAKRK VQKEQADKLA REHGIRFFET

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-RAB13 Antibody Picoband® (ABIN3043916). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human RAB13, different from the related mouse and rat sequences by four amino acids.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. "Entrez Gene: RAB13 RAB13, member RAS oncogene family". 2. Zahraoui A, Joberty G, Arpin M, Fontaine JJ, Hellio R, Tavitian A, Louvard D (Feb 1994). "A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells". J Cell Biol 124 (1-2): 101-15.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

    Andere Bezeichnung

    RAB13

    Hintergrund

    Synonyms: Ras-related protein Rab-13,Cell growth-inhibiting gene 4 protein,RAB13,GIG4,

    Tissue Specificity: Detected in several types of epithelia, including intestine, kidney, liver and in endothelial cells.

    Background: Ras-related protein Rab-13 is a protein that in humans is encoded by the RAB13 gene. This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12.

    Molekulargewicht

    23 kDa

    Gen-ID

    5872

    UniProt

    P51153

    Pathways

    Cell-Cell Junction Organization
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