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BMP6 Antikörper (C-Term)

BMP6 Reaktivität: Human WB, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3043760
  • Target Alle BMP6 Antikörper anzeigen
    BMP6 (Bone Morphogenetic Protein 6 (BMP6))
    Bindungsspezifität
    • 6
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 383-419, C-Term
    Reaktivität
    • 45
    • 14
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 42
    • 9
    Kaninchen
    Klonalität
    • 40
    • 11
    Polyklonal
    Konjugat
    • 27
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BMP6 Antikörper ist unkonjugiert
    Applikation
    • 35
    • 23
    • 16
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    Anti-BMP6 Antibody Picoband®
    Sequenz
    QSRNRSTQSQ DVARVSSASD YNSSELKTAC RKHELYV
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-BMP6 Antibody Picoband® (ABIN3043760). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human BMP6, different from the related mouse sequence by six amino acids, and from the related rat sequence by three amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product BMP6 Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. "Entrez Gene: BMP6 bone morphogenetic protein 6". 2. Hahn GV, Cohen RB, Wozney JM, Levitz CL, Shore EM, Zasloff MA, Kaplan FS (Dec 1992). "A bone morphogenetic protein subfamily: chromosomal localization of human genes for BMP5, BMP6, and BMP7". Genomics 14 (3): 759-62. 3. Sauermann U, Meyermann R, Schluesener HJ (Jan 1993). "Cloning of a novel TGF-beta related cytokine, the vgr, from rat brain: cloning of and comparison to homologous human cytokines". J Neurosci Res 33 (1): 142-7.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Tang, Li, Yu, Gao, Liu, Chen, Xing, Liu, Yao: "Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway." in: The Journal of nutritional biochemistry, Vol. 25, Issue 6, pp. 675-82, (2014) (PubMed).

  • Target
    BMP6 (Bone Morphogenetic Protein 6 (BMP6))
    Andere Bezeichnung
    BMP6 (BMP6 Produkte)
    Hintergrund

    Synonyms: Bone morphogenetic protein 6,BMP-6,VG-1-related protein,VG-1-R,VGR-1,BMP6,VGR,

    Tissue Specificity: Expressed in the lung and liver.

    Background: Bone morphogenetic protein 6?is a?protein?that in humans is encoded by the?BMP6?gene. It is mapped to 6p24-p23. The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

    Molekulargewicht
    43 kDa
    Gen-ID
    654
    UniProt
    P22004
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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