Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

BMP6 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-BMP6-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, BMP6 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN3043760

Kurzübersicht für BMP6 Antikörper (C-Term) (ABIN3043760)

Target

Alle BMP6 Antikörper anzeigen
BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Reaktivität

  • 61
  • 20
  • 17
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 56
  • 18
Kaninchen

Klonalität

  • 54
  • 20
Polyklonal

Konjugat

  • 44
  • 13
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BMP6 Antikörper ist unkonjugiert

Applikation

  • 57
  • 38
  • 23
  • 21
  • 14
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 9
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 383-419, C-Term

    Verwendungszweck

    Anti-BMP6 Antibody Picoband®

    Sequenz

    QSRNRSTQSQ DVARVSSASD YNSSELKTAC RKHELYV

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-BMP6 Antibody Picoband® (ABIN3043760). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human BMP6, different from the related mouse sequence by six amino acids, and from the related rat sequence by three amino acids.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. "Entrez Gene: BMP6 bone morphogenetic protein 6". 2. Hahn GV, Cohen RB, Wozney JM, Levitz CL, Shore EM, Zasloff MA, Kaplan FS (Dec 1992). "A bone morphogenetic protein subfamily: chromosomal localization of human genes for BMP5, BMP6, and BMP7". Genomics 14 (3): 759-62. 3. Sauermann U, Meyermann R, Schluesener HJ (Jan 1993). "Cloning of a novel TGF-beta related cytokine, the vgr, from rat brain: cloning of and comparison to homologous human cytokines". J Neurosci Res 33 (1): 142-7.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Tang, Li, Yu, Gao, Liu, Chen, Xing, Liu, Yao: "Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway." in: The Journal of nutritional biochemistry, Vol. 25, Issue 6, pp. 675-82, (2014) (PubMed).

  • Target

    BMP6 (Bone Morphogenetic Protein 6 (BMP6))

    Andere Bezeichnung

    BMP6

    Hintergrund

    Synonyms: Bone morphogenetic protein 6,BMP-6,VG-1-related protein,VG-1-R,VGR-1,BMP6,VGR,

    Tissue Specificity: Expressed in the lung and liver.

    Background: Bone morphogenetic protein 6?is a?protein?that in humans is encoded by the?BMP6?gene. It is mapped to 6p24-p23. The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.

    Molekulargewicht

    43 kDa

    Gen-ID

    654

    UniProt

    P22004

    Pathways

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
Sie sind hier:
Chat with us!