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CCL1 Antikörper (AA 24-96)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CCL1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 4+ Publikationen erwähnt.
Produktnummer ABIN3043738

Kurzübersicht für CCL1 Antikörper (AA 24-96) (ABIN3043738)

Target

Alle CCL1 Antikörper anzeigen
CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))

Reaktivität

  • 46
  • 7
  • 2
  • 1
Human

Wirt

  • 44
  • 7
  • 1
  • 1
  • 1
Kaninchen

Klonalität

  • 47
  • 7
Polyklonal

Konjugat

  • 32
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CCL1 Antikörper ist unkonjugiert

Applikation

  • 44
  • 13
  • 13
  • 13
  • 11
  • 10
  • 9
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-96

    Verwendungszweck

    Anti-I-309/CCL1 IGF1R Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-I-309/CCL1 IGF1R Antibody Picoband® (ABIN3043738). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human I-309 recombinant protein (Position: K24-K96). Human I-309 shares 38% amino acid (aa) sequence identity with mouse I-309.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, -
    ELISA, 0.1-0.5 μg/mL, -
    1. Miller, M. D., Wilson, S. D., Dorf, M. E., Seuanez, H. N., O'Brien, S. J., Krangel, M. S.Sequence and chromosomal location of the I-309 gene: relationship to genes encoding a family of inflammatory cytokines.J. Immun. 145: 2737-2744, 1990.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Li, Chen, Liu, Hou: "Long-pulse gastric electrical stimulation protects interstitial cells of Cajal in diabetic rats via IGF-1 signaling pathway." in: World journal of gastroenterology, Vol. 22, Issue 23, pp. 5353-63, (2017) (PubMed).

    Hou, Wan, Wang, Li, Wang, Yao, Feng, Jing, Lu, Jia, Peng: "Let-7a inhibits migration of melanoma cells via down-regulation of HMGA2 expression." in: American journal of translational research, Vol. 8, Issue 9, pp. 3656-3665, (2016) (PubMed).

    Liang, Hao, Zhang, Wu, Wang: "Insulin-like growth factors in endometrioid adenocarcinoma: correlation with clinico-pathological features and estrogen receptor expression." in: BMC cancer, Vol. 12, pp. 262, (2013) (PubMed).

    Zhang, Leng, Wang, Zhang: "Treating human meniscal fibrochondrocytes with hIGF-1 gene by liposome." in: Clinical orthopaedics and related research, Vol. 467, Issue 12, pp. 3175-82, (2010) (PubMed).

  • Target

    CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))

    Andere Bezeichnung

    CCL1

    Hintergrund

    Synonyms: Insulin-like growth factor 1 receptor,2.7.10.1,Insulin-like growth factor I receptor,IGF-I receptor,CD221,Insulin-like growth factor 1 receptor alpha chain,Insulin-like growth factor 1 receptor beta chain,IGF1R,

    Tissue Specificity: Found as a hybrid receptor with INSR in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Expressed in a variety of tissues. Overexpressed in tumors, including melanomas, cancers of the colon, pancreas prostate and kidney. .

    Background: CCL1, Chemokine (C-C motif) ligand 1, is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8.

    Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

    Molekulargewicht

    11 kDa

    Gen-ID

    6346

    UniProt

    P08069
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