CCR6 Antikörper (C-Term)

Produktnummer ABIN3043702

Produktdetails anti-CCR6 Antikörper

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Bindungsspezifität: AA 358-374, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for C-C chemokine receptor type 6(CCR6) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: RQTSETADND NASSFTM

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for C-C chemokine receptor type 6(CCR6) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: chemokine(C-C motif) receptor 6
Protein Name: C-C chemokine receptor type 6(C-C CKR-6/CC-CKR-6/CCR-6)

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CCR6(358-374aa RQTSETADNDNASSFTM), different from the related rat and mouse sequences by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu CCR6

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Andere Bezeichnung: CCR6 (CCR6 Produkte)

Synonyme: BN-1 antikoerper, C-C CKR-6 antikoerper, CC-CKR-6 antikoerper, CCR-6 antikoerper, CD196 antikoerper, CKR-L3 antikoerper, CKRL3 antikoerper, CMKBR6 antikoerper, DCR2 antikoerper, DRY6 antikoerper, GPR29 antikoerper, GPRCY4 antikoerper, STRL22 antikoerper, Cmkbr6 antikoerper, KY411 antikoerper, C-C motif chemokine receptor 6 antikoerper, chemokine (C-C motif) receptor 6 antikoerper, CCR6 antikoerper, Ccr6 antikoerper

Hintergrund: CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.

Synonyms: BN 1 antibody|BN1 antibody|C C chemokine receptor type 6 antibody|C C CKR 6 antibody|C-C chemokine receptor type 6 antibody|C-C CKR-6 antibody|CC chemokine receptor type 6 antibody|CC CKR 6 antibody|CC R6 antibody|CC-CKR-6 antibody|CCCKR6 antibody|CCR 6 antibody|CCR-6 antibody|Ccr6 antibody|CCR6_HUMAN antibody|CD 196 antibody|CD196 antibody|CD196 antigen antibody|Chemokine(C C motif) receptor 6 antibody|Chemokine(C C) receptor 6 antibody|Chemokine(CC motif) receptor 6 antibody|Chemokine(CC) receptor 6 antibody|Chemokine receptor 6 antibody|Chemokine receptor like 3 antibody|Chemokine receptor-like 3 antibody|CKR 6 antibody|CKR L3 antibody|CKR-L3 antibody|CKR6 antibody|CKRL3 antibody|CMKBR6 antibody|CMKBR6 antibody|DCR 2 antibody|DCR2 antibody|DRY 6 antibody|DRY6 antibody|G protein coupled receptor 29 antibody|G-protein coupled receptor 29 antibody|GPR 29 antibody|GPR CY4 antibody|GPR-CY4 antibody|GPR29 antibody|GPRCY 4 antibody|GPRCY4 antibody|LARC receptor antibody|Seven transmembrane receptor lymphocyte 22 antibody|STRL 22 antibody|STRL22 antibody

UniProt: P51684

Pathways: cAMP Metabolic Process