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PIM1 Antikörper (C-Term)

PIM1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3043606
  • Target Alle PIM1 Antikörper anzeigen
    PIM1 (Pim-1 Oncogene (PIM1))
    Bindungsspezifität
    • 19
    • 16
    • 14
    • 8
    • 8
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 373-404, C-Term
    Reaktivität
    • 103
    • 48
    • 47
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 104
    • 9
    Kaninchen
    Klonalität
    • 93
    • 20
    Polyklonal
    Konjugat
    • 46
    • 16
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PIM1 Antikörper ist unkonjugiert
    Applikation
    • 95
    • 52
    • 28
    • 27
    • 26
    • 18
    • 14
    • 9
    • 6
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase pim-1(PIM1) detection. Tested with WB in Human.
    Sequenz
    EEIQNHPWMQ DVLLPQETAE IHLHSLSPGP SK
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase pim-1(PIM1) detection. Tested with WB in Human.
    Gene Name: Pim-1 proto-oncogene, serine/threonine kinase
    Protein Name: Serine/threonine-protein kinase pim-1
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human PIM1(373-404aa EEIQNHPWMQDVLLPQETAEIHLHSLSPGPSK), different from the related mouse sequence by seven amino acids and from the related rat sequence by two amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product PIM1 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for PIM1 is approximately 0.1 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Wu, Lu, He, Jin: "PIM1 polymorphism and PIM1 expression as predisposing factors of esophageal squamous cell carcinoma in the Asian population." in: OncoTargets and therapy, Vol. 9, pp. 2919-25, (2016) (PubMed).

  • Target
    PIM1 (Pim-1 Oncogene (PIM1))
    Andere Bezeichnung
    PIM1 (PIM1 Produkte)
    Synonyme
    PIM antikoerper, Pim-1 antikoerper, PIM1 antikoerper, pim antikoerper, pim-1 antikoerper, pim3 antikoerper, Pim-1 proto-oncogene, serine/threonine kinase antikoerper, proviral integration site 1 antikoerper, Pim-1 proto-oncogene, serine/threonine kinase L homeolog antikoerper, PIM1 antikoerper, Pim1 antikoerper, pim1 antikoerper, pim1.L antikoerper
    Hintergrund
    Proto-oncogene serine/threonine-protein kinase Pim-1 is an enzyme that in humans is encoded by the PIM1 gene. It is mapped to 6p21.2. Primarily expressed in spleen, thymus, bone marrow, prostate, oral epithelial, hippocampus and fetal liver cells, Pim-1 has also been found to be highly expressed in cell cultures isolated from human tumors. Pim-1 is mainly involved in cell cycle progression, apoptosis and transcriptional activation, as well as more general signal transduction pathways. It has been found a physiologic role of the PIM1 oncogene during hematopoietic development and a deregulation of the gene in various leukemias. PIM1 also has a role in cardioprotection downstream of AKT activation.

    Synonyms: Oncogene PIM 1 antibody|Oncogene PIM1 antibody|PIM 1 antibody|pim 1 kinase 44 kDa isoform antibody|Pim 1 kinase antibody|pim 1 oncogene (proviral integration site 1) antibody|Pim 1 oncogene antibody|PIM antibody|PIM1 antibody|pim1 kinase 44 kDa isoform antibody|PIM1_HUMAN antibody|Pim2 antibody|PIM3 antibody|Proto oncogene serine/threonine protein kinase Pim 1 antibody|Proto-oncogene serine/threonine-protein kinase Pim-1 antibody|Proviral integration site 1 antibody|Proviral integration site 2 antibody
    Gen-ID
    5292
    UniProt
    P11309
    Pathways
    Glycosaminoglycan Metabolic Process
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