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Parvin alpha Antikörper (Middle Region)

Dieses Anti-Parvin alpha-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Parvin alpha in WB und IHC. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN3043590

Kurzübersicht für Parvin alpha Antikörper (Middle Region) (ABIN3043590)

Target

Alle Parvin alpha (PARVA) Antikörper anzeigen
Parvin alpha (PARVA) (Parvin, alpha (PARVA))

Reaktivität

  • 37
  • 30
  • 4
  • 3
  • 2
Human, Maus, Ratte

Wirt

  • 47
  • 6
  • 1
Kaninchen

Klonalität

  • 49
  • 5
Polyklonal

Konjugat

  • 26
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Parvin alpha Antikörper ist unkonjugiert

Applikation

  • 48
  • 26
  • 15
  • 13
  • 13
  • 9
  • 7
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 16
    • 8
    • 8
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 155-185, Middle Region

    Verwendungszweck

    Anti-Parvin alpha/PARVA Antibody Picoband®

    Sequenz

    QKLQTVLEKI NETLKLPPRS IKWNVDSVHA K

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Parvin alpha/PARVA Antibody Picoband® (ABIN3043590). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence in the middle region of human Parvin alpha, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

    Isotyp

    IgG
  • Applikationshinweise

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene: PARVA parvin, alpha". 2. Olski TM, Noegel AA, Korenbaum E (Feb 2001). "Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily". J Cell Sci 114 (Pt 3): 525-38. 3. Zhang Y, Chen K, Tu Y, Wu C (2004). "Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival.". J. Biol. Chem. 279 (40): 41695-705.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    Parvin alpha (PARVA) (Parvin, alpha (PARVA))

    Andere Bezeichnung

    PARVA

    Hintergrund

    Synonyms: Alpha-parvin,Actopaxin,CH-ILKBP,Calponin-like integrin-linked kinase-binding protein,Matrix-remodeling-associated protein 2,PARVA,MXRA2,

    Tissue Specificity: Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. .

    Background: Parvin alpha is a protein that in humans is encoded by the PARVA gene. It is located on 11p15.3. PARVA belongs to the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival.

    Sequence Similarities: Belongs to the parvin family.

    Molekulargewicht

    42 kDa

    Gen-ID

    55742

    Pathways

    Smooth Muscle Cell Migration
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