RAB3A Antikörper (C-Term)

Produktnummer ABIN3043559

Produktdetails anti-RAB3A Antikörper

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Bindungsspezifität: AA 192-220, C-Term

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Ras-related protein Rab-3A(RAB3A) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: DTADPAVTGA KQGPQLSDQQ VPPHQDCAC

Kreuzreaktivität (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Ras-related protein Rab-3A(RAB3A) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: RAB3A, member RAS oncogene family
Protein Name: Ras-related protein Rab-3A

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Rab3A (192-220aa DTADPAVTGAKQGPQLSDQQVPPHQDCAC), different from the related mouse and rat sequences by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, The detection limit for Rab3A is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu RAB3A

Target: RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))

Andere Bezeichnung: RAB3A (RAB3A Produkte)

Synonyme: RAB3 antikoerper, rab3a antikoerper, zgc:92276 antikoerper, RAB3A antikoerper, rab-3a antikoerper, si:ch211-255d18.4 antikoerper, zgc:112516 antikoerper, RAB3A, member RAS oncogene family antikoerper, RAB3A, member RAS oncogene family, a antikoerper, RAB3A, member RAS oncogene family L homeolog antikoerper, RAB3A, member RAS oncogene family, b antikoerper, RAB3A antikoerper, Rab3a antikoerper, rab3aa antikoerper, rab3a.L antikoerper, rab3a antikoerper, rab3ab antikoerper

Hintergrund: Ras-related protein Rab-3A is a protein that in humans is encoded by the RAB3A gene. This gene is mapped to 19p13.11. Synapsin I stimulated the RAB3A cycle by increasing GTP binding, GTPase activity, and RAB3A recruitment to the synaptic vesicle membrane. Conversely, RAB3A inhibited synapsin I binding to actin and synapsin I-induced synaptic vesicle clustering. It has been found that RAB3A was necessary for both forms of synaptic plasticity, and it is also involved in calcium exocytosis in neurons. In addition to that, RAB3A has been found to regulate a late step in synaptic vesicle fusion.

Synonyms: Rab 3A antibody|RAB 3A member RAS oncogene family antibody|Rab3a antibody|RAB3A member RAS oncogene family antibody|RAB3A_HUMAN antibody|RAS associated protein RAB 3A antibody|RAS associated protein RAB3A antibody|Ras related protein Rab 3A antibody|Ras related protein Rab3A antibody|Ras-related protein Rab-3A antibody

Gen-ID: 5864

UniProt: P20336

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport