RAB10 Antikörper (C-Term)

Produktnummer ABIN3043448

Der Kaninchen Polyklonal Anti-RAB10-Antikörper wurde für WB validiert. Er ist geeignet, RAB10 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für RAB10 Antikörper (C-Term) (ABIN3043448)

Target: RAB10 (RAB10, Member RAS Oncogene Family (RAB10))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RAB10 Antikörper

Bindungsspezifität: AA 153-185, C-Term

Verwendungszweck: Anti-RAB10 Antibody Picoband®

Sequenz: AKANINIEKA FLTLAEDILR KTPVKEPNSE NVD

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-RAB10 Antibody Picoband® (ABIN3043448). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human RAB10, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: RAB10 RAB10, member RAS oncogene family". 2. Chen YT, Holcomb C, Moore HP (Aug 1993). "Expression and localization of two low molecular weight GTP-binding proteins, Rab8 and Rab10, by epitope tag". Proc Natl Acad Sci U S A 90 (14): 6508-12. 3. He, H., Dai, F., Yu, L., She, X., Zhao, Y., Jiang, J., Chen, X., Zhao, S. Identification and characterization of nine novel human small GTPases showing variable expressions in liver cancer tissues. Gene Expr. 10: 231-242, 2002.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu RAB10

Target: RAB10 (RAB10, Member RAS Oncogene Family (RAB10))

Andere Bezeichnung: RAB10

Hintergrund:

Synonyms: Ras-related protein Rab-10,RAB10,

Tissue Specificity: Expressed in breast, placenta, kidney, liver and pancreas. .

Background: Ras-related protein Rab-10 is a protein that in humans is encoded by the RAB10 gene. RAB10 belongs to the RAS superfamily of small GTPases. And RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking. The RAB10 gene is mapped to chromosome 2p23.1-p22.3 by radiation hybrid analysis. It was found that the purified recombinant GAP domain of human AS160 showed GAP activity with RAB2A, RAB8A, RAB10, and RAB14, but not with 14 other RABs. Immunoblot analysis showed that these RABs associated with Glut4-positive vesicles in mouse adipocytes. Thereby, it concluded that AK160 functions as a RAB GAP and that RABs may participate in GLUT4 translocation.

Molekulargewicht: 23 kDa

Gen-ID: 10890

UniProt: P61026

Pathways: Asymmetric Protein Localization, SARS-CoV-2 Protein Interaktom