SHBG Antikörper (AA 30-210)

Produktnummer ABIN3043434

Produktdetails anti-SHBG Antikörper

Target: SHBG (Sex Hormone Binding Globulin (SHBG))

Bindungsspezifität: AA 30-210

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHBG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Sex hormone-binding globulin(SHBG) detection. Tested with WB in Human.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Sex hormone-binding globulin(SHBG) detection. Tested with WB in Human.
Gene Name: sex hormone-binding globulin
Protein Name: Sex hormone-binding globulin

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SHBG recombinant protein (Position: L30-A210). Human SHBG shares 72% amino acid (aa) sequence identity with both mouse and rat SHBG.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SHBG is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu SHBG

Target: SHBG (Sex Hormone Binding Globulin (SHBG))

Andere Bezeichnung: SHBG (SHBG Produkte)

Hintergrund: Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to the sex hormones,androgen and estrogen. SHBG is produced mostly by the liver and is released into the bloodstream. Other sites that produce SHBG include the brain, uterus, testes, and placenta. SHBG has both enhancing and inhibiting hormonal influences. It decreases with high levels of insulin, growth hormone, insulin-like growth factor 1 (IGF-1), androgens, prolactin and transcortin. High estrogen, andthyroxine cause it to increase. It has been found that the monosaccharides glucose and fructose reduced human SHBG production by hepatocytes, irrespective of the presence of insulin, by downregulation of hepatocyte nuclear factor-4A and replacement of HNF4A by COUP-TFI at a cis-element within the human SHBG promoter, coincident with repression of its transcriptional activity.

Synonyms: ABP antibody|Androgen binding protein antibody|SBP antibody|Sex hormone-binding globulin antibody|Sex steroid binding protein antibody|Sex steroid-binding protein antibody|SHBG antibody|SHBG_HUMAN antibody|TeBG antibody|Testis specific androgen binding protein antibody|Testis-specific androgen-binding protein antibody|Testosterone binding beta globulin antibody|Testosterone estradiol binding globulin antibody|Testosterone estrogen binding globulin antibody|Testosterone-estradiol-binding globulin antibody|Testosterone-estrogen-binding globulin antibody

Gen-ID: 6462

UniProt: P04278

Pathways: Hormone Transport