STXBP1 Antikörper (N-Term)
Kurzübersicht für STXBP1 Antikörper (N-Term) (ABIN3043413)
Target
Alle STXBP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- AA 184-216, N-Term
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                                            Verwendungszweck
- Anti-Munc18-1/STXBP1 Antibody Picoband®
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                                            Sequenz
- KEYPAVRYRG EYKDNALLAQ LIQDKLDAYK ADD
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                                            Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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                                            Produktmerkmale
- Anti-Munc18-1/STXBP1 Antibody Picoband® (ABIN3043413). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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                                            Aufreinigung
- Immunogen affinity purified.
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                                            Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human Munc18-1, identical to the related mouse and rat sequences.
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                                            Isotyp
- IgG
 
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                                            Applikationshinweise
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                        Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
 Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
 Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
 Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
 1. "Entrez Gene: STXBP1 syntaxin binding protein 1". 2. Fisher, R. J., Pevsner, J., Burgoyne, R. D. Control of fusion pore dynamics during exocytosis by Munc18. Science 291: 875-878, 2001. 3. Swanson DA, Steel JM, Valle D (Jun 1998). "Identification and characterization of the human ortholog of rat STXBP1, a protein implicated in vesicle trafficking and neurotransmitter release". Genomics 48 (3): 373-6.
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                                            Kommentare
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                        Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P). 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Lyophilized
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                                            Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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                                            Konzentration
- 500 μg/mL
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                                            Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Handhabung
- Avoid repeated freezing and thawing.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
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                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
 
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    - STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
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                                            Andere Bezeichnung
- STXBP1
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                                            Hintergrund
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                        Synonyms: Syntaxin-binding protein 1,MUNC18-1,N-Sec1,Protein unc-18 homolog 1,Unc18-1,Protein unc-18 homolog A,Unc-18A,p67,STXBP1,UNC18A, Tissue Specificity: Brain and spinal cord. Highly enriched in axons. Background: Syntaxin-binding protein 1, also known as Munc18-1, is a protein that in humans is encoded by the STXBP1 gene. By fluorescence in situ hybridization, the STXBP1 gene is mapped to chromosome 9q34.1. This gene encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described. 
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                                            Molekulargewicht
- 70 kDa
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                                            Gen-ID
- 6812
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                                            UniProt
- P61764
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                                            Pathways
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
 Target
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