OMG Antikörper (N-Term)

Produktnummer ABIN3043375

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch OMG in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für OMG Antikörper (N-Term) (ABIN3043375)

Target: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OMG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-OMG Antikörper

Bindungsspezifität: AA 64-99, N-Term

Verwendungszweck: Anti-Oligodendrocyte myelin glycoprotein/OMG Antibody Picoband®

Sequenz: YNHFTDLHNQ LTQYTNLRTL DISNNRLESL PAHLPR

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Oligodendrocyte myelin glycoprotein/OMG Antibody Picoband® (ABIN3043375). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human OMG, different from the related mouse sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: OMG oligodendrocyte myelin glycoprotein". 2. Mikol DD, Alexakos MJ, Bayley CA, Lemons RS, Le Beau MM, Stefansson K (Mar 1991). "Structure and chromosomal localization of the gene for the oligodendrocyte-myelin glycoprotein". J Cell Biol 111 (6 Pt 1): 2673-9. 3. Viskochil D, Cawthon R, O'Connell P, Xu GF, Stevens J, Culver M, Carey J, White R (Mar 1991). "The gene encoding the oligodendrocyte-myelin glycoprotein is embedded within the neurofibromatosis type 1 gene". Mol Cell Biol 11 (2): 906-12.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu OMG

Target: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Andere Bezeichnung: OMG

Hintergrund:

Synonyms: Oligodendrocyte-myelin glycoprotein,OMG,OMGP,

Tissue Specificity: Oligodendrocytes and myelin of the central nervous system.

Background: Oligodendrocyte-myelin glycoprotein is a protein that in humans is encoded by the OMG gene. This gene is mapped to 17q11-q12. OMG, like neurofibromin (NF1), has growth suppressive effects and downregulates mitogenic signaling pathways closely related to those influenced by neurofibromin. Overexpression of OMG alters mitogenic signaling in fibroblasts. Cells overexpressing OMG grow more slowly in serum compared to controls and show a partial G1 block upon cell cycle analysis.

Molekulargewicht: 50 kDa

Gen-ID: 4974

UniProt: P23515

Pathways: Neurotrophin Signalübertragung, Regulation of Cell Size