Sp2 Antikörper (Middle Region)

Produktnummer ABIN3043349

Der Kaninchen Polyklonal Anti-Sp2-Antikörper wurde für WB validiert. Er ist geeignet, Sp2 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für Sp2 Antikörper (Middle Region) (ABIN3043349)

Target: Sp2 (Sp2 Transcription Factor (Sp2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sp2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Sp2 Antikörper

Bindungsspezifität: AA 312-343, Middle Region

Verwendungszweck: Anti-SP2 transcription factor Antibody Picoband®

Sequenz: QVVQIPQQAL RVVQAASATL PTVPQKPSQN FQ

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-SP2 transcription factor Antibody Picoband® (ABIN3043349). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SP2, identical to the related mouse sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Kingsley C, Winoto A (Oct 1992). "Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression". Mol Cell Biol 12 (10): 4251-61. 2. Rotheneder H, Geymayer S, Haidweger E (Nov 1999). "Transcription factors of the Sp1 family: interaction with E2F and regulation of the murine thymidine kinase promoter". J. Mol. Biol. 293 (5): 1005-15. 3. Scohy S, Van Vooren P, Szpirer C, Szpirer J (Oct 1998). "Assignment1 of Sp genes to rat chromosome bands 7q36 (Sp1), 10q31→q32.1 (Sp2), 3q24→q31 (Sp3) and 6q33 (Sp4) and of the SP2 gene to human chromosome bands 17q21.3→q22 by in situ hybridization". Cytogenet Cell Genet 81 (3-4): 273-4.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu Sp2

Target: Sp2 (Sp2 Transcription Factor (Sp2))

Andere Bezeichnung: SP2

Hintergrund:

Synonyms: Transcription factor Sp2,SP2,KIAA0048,

Tissue Specificity: Most abundant in lung, less in heart and skin. .

Background: Transcription factor Sp2 is a protein that in humans is encoded by the SP2 gene. This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters.

Sequence Similarities: Belongs to the Sp1 C2H2-type zinc-finger protein family.

Molekulargewicht: 72 kDa

Gen-ID: 6668

UniProt: Q02086