L-Selectin Antikörper (AA 39-372)

Produktnummer ABIN3043326

Dieses Anti-L-Selectin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von L-Selectin in WB, IHC und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für L-Selectin Antikörper (AA 39-372) (ABIN3043326)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser L-Selectin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-L-Selectin Antikörper

Bindungsspezifität: AA 39-372

Verwendungszweck: Anti-CD62L/SELL Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-CD62L/SELL Antibody Picoband® (ABIN3043326). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human L-selectin recombinant protein (Position: W39-Y372). Human L-selectin shares 77.5 % and 78.7 % amino acid (aa) sequence identity with mouse and rat L-selectin, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: SELL selectin L (lymphocyte adhesion molecule 1)". 2. Cotran, Kumar, Collins (1998). Robbins Pathologic Basis of Disease. Philadelphia: W.B Saunders Company.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Andere Bezeichnung: SELL

Hintergrund:

Synonyms: L-selectin,CD62 antigen-like family member L,Leukocyte adhesion molecule 1,LAM-1,Leukocyte surface antigen Leu-8,Leukocyte-endothelial cell adhesion molecule 1,LECAM1,Lymph node homing receptor,TQ1,gp90-MEL,CD62L,SELL,LNHR, LYAM1,

Tissue Specificity: Expressed in B-cell lines and T-lymphocytes. .

Background: CD62L, also known as L-selectin, is a cell adhesion molecule found on leukocytes. It belongs to the selectin family of proteins, which recognize sialylated carbohydrate groups. It is cleaved by ADAM17. SELL (L-selectin) is a cell surface component that is a member of a family of adhesion/homing receptors which play important roles in leukocyte-endothelial cell interactions. The molecule is composed of multiple domains: one homologous to lectins, one to epidermal growth factor, and two to the consensus repeat units found in C3/C4 binding proteins. L-selectin acts as a "homing receptor" for leukocytes to enter secondary lymphoid tissues via high endothelial venules. Ligands present on endothelial cells will bind to leukocyte expressing L-selectin, slowing leukocyte trafficking through the blood, and facilitating entry into a secondary lymphoid organ at that point.

Sequence Similarities: Belongs to the selectin/LECAM family.

Molekulargewicht: 42 kDa

Gen-ID: 6402

UniProt: P14151