Sectm1b Antikörper (C-Term)

Produktnummer ABIN3043325

Der Kaninchen Polyklonal anti-Sectm1b Antikörper wird verwendet zum Nachweis von Sectm1b in Proben von Maus. Er wurde validiert für WB.

Kurzübersicht für Sectm1b Antikörper (C-Term) (ABIN3043325)

Target: Sectm1b (SECTM1B) (Secreted and Transmembrane 1B (SECTM1B))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Western Blotting (WB)

Produktdetails anti-Sectm1b Antikörper

Bindungsspezifität: AA 118-152, C-Term

Verwendungszweck: Anti-SECTM1/Sectm1b Antibody

Sequenz: KLHGFQAEFK NFNLTVNAAD RQKTEDLPVT KVPDK

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-SECTM1/Sectm1b Antibody (ABIN3043325). Tested in WB applications. This antibody reacts with Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse SECTM1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Mouse

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu Sectm1b

Target: Sectm1b (SECTM1B) (Secreted and Transmembrane 1B (SECTM1B))

Andere Bezeichnung: Sectm1b

Hintergrund:

Synonyms: Secreted and transmembrane protein 1b,Protein K-12,Sectm1b,K12, Sectm1,

Tissue Specificity: Calprotectin (S100A8/9) is predominantly expressed in myeloid cells. Except for inflammatory conditions, the expression is restricted to a specific stage of myeloid differentiation since both proteins are expressed in circulating neutrophils and monocytes but are absent in normal tissue macrophages and lymphocytes. Under chronic inflammatory conditions, such as psoriasis and malignant disorders, also expressed in the epidermis. Found in high concentrations at local sites of inflammation or in the serum of patients with inflammatory diseases such as rheumatoid, cystic fibrosis, inflammatory bowel disease, Crohn's disease, giant cell arteritis, cystic fibrosis, Sjogren's syndrome, systemic lupus erythematosus, and progressive systemic sclerosis. Involved in the formation and deposition of amyloids in the aging prostate known as corpora amylacea inclusions. Strongly up-regulated in many tumors, including gastric, esophageal, colon, pancreatic, bladder, ovarian, thyroid, breast and skin cancers. .

Background: SECTM1B is also known as Sectm1 or K12. Secreted and transmembrane protein 1 is a protein that in humans is encoded by the SECTM1 gene. This gene encodes a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein. It is found in a perinuclear Golgi-like pattern and thought to be involved in hematopoietic and/or immune system processes.

Molekulargewicht: 23 kDa

Gen-ID: 58210