NAE1 Antikörper (AA 181-534)

Produktnummer ABIN3043281

Produktdetails anti-NAE1 Antikörper

Target: NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Bindungsspezifität: AA 181-534

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for NEDD8-activating enzyme E1 regulatory subunit(NAE1) detection. Tested with WB in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for NEDD8-activating enzyme E1 regulatory subunit(NAE1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: NEDD8 activating enzyme E1 subunit 1
Protein Name: NEDD8-activating enzyme E1 regulatory subunit

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human APPBP1 recombinant protein (Position: E181-L534). Human APPBP1 shares 98% amino acid (aa) sequence identity with mouse APPBP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for APPBP1 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu NAE1

Target: NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))

Andere Bezeichnung: NAE1 (NAE1 Produkte)

Synonyme: APPBP1 antikoerper, CG7828 antikoerper, Dmel\\CG7828 antikoerper, anon-WO0140519.225 antikoerper, dAPP-BP1 antikoerper, dAPPBP1 antikoerper, A-116A10.1 antikoerper, ula-1 antikoerper, Appbp1 antikoerper, 59kDa antikoerper, appbp1 antikoerper, zgc:66148 antikoerper, beta-Amyloid precursor protein binding protein 1 antikoerper, NEDD8 activating enzyme E1 subunit 1 antikoerper, NEDD8 activating enzyme E1 subunit 1 S homeolog antikoerper, nedd8 activating enzyme E1 subunit 1 antikoerper, NEDD8-activating enzyme E1 regulatory subunit antikoerper, APP-BP1 antikoerper, NAE1 antikoerper, Nae1 antikoerper, nae1.S antikoerper, nae1 antikoerper, ula-1 antikoerper

Hintergrund: NAE1 is also known as APPBP1. The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.

Synonyms: 59 kDa antibody|A 116A10.1 antibody|Amyloid beta precursor protein binding protein 1 59kD antibody|Amyloid beta precursor protein binding protein 1 59 kDa antibody|Amyloid beta precursor protein binding protein 1 antibody|Amyloid beta precursor protein-binding protein 1 antibody|Amyloid protein binding protein 1 antibody|Amyloid protein-binding protein 1 antibody|APP BP1 antibody|APP-BP1 antibody|APPBP 1 antibody|HPP 1 antibody|HPP1 antibody|NAE 1 antibody|NAE1 antibody|NEDD8 activating enzyme E1 regulatory subunit antibody|NEDD8 activating enzyme E1 subunit 1 antibody|NEDD8 activating enzyme E1 subunit antibody|NEDD8-activating enzyme E1 regulatory subunit antibody|Proto oncogene protein 1 antibody|Proto-oncogene protein 1 antibody|Protooncogene protein 1 antibody|ula 1 antibody|ULA1_HUMAN antibody

Gen-ID: 8883

UniProt: Q13564