DGAT1 Antikörper (Middle Region)

Produktnummer ABIN3043266

Dieser Anti-DGAT1-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von DGAT1 in WB. Geeignet für Human und Ratte.

Kurzübersicht für DGAT1 Antikörper (Middle Region) (ABIN3043266)

Target: DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DGAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DGAT1 Antikörper

Bindungsspezifität: AA 280-318, Middle Region

Verwendungszweck: Anti-DGAT1 Antibody

Sequenz: RRILEMLFFT QLQVGLIQQW MVPTIQNSMK PFKDMDYSR

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-DGAT1 Antibody (ABIN3043266). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human DGAT1, different from the related mouse and rat sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu DGAT1

Target: DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))

Andere Bezeichnung: DGAT1

Hintergrund:

Synonyms: Diacylglycerol O-acyltransferase 1,2.3.1.20 ,ACAT-related gene product 1,Acyl-CoA retinol O-fatty-acyltransferase,ARAT,Retinol O-fatty-acyltransferase,2.3.1.76 ,Diglyceride acyltransferase,DGAT1,AGRP1, DGAT,

Tissue Specificity: Widely expressed.

Background: Acyl-CoA: diacylglycerol acyltransferase (DGAT) is a microsomal enzyme that plays a central role in the metabolism of cellular diacylglycerol lipids and catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol (DAG) and fatty acyl CoA as substrates. DGAT had been considered necessary for adipose tissue formation and essential for survival. There are two isozymes of DGAT encoded by the genes DGAT1 and DGAT2. DGAT1 is a host factor for HCV infection that binds core protein, localizes it to DGAT1-generated lipid droplets, and recruits viral RNA replication complexes for viral assembly. DGAT2-generated lipid droplets formed normally in cells treated with the DGAT1 inhibitor, suggesting that DGAT1 inhibitors may be useful as antiviral therapeutics.

Molekulargewicht: 60 kDa

Gen-ID: 8694

UniProt: O75907

Pathways: Hormone Transport