beta Defensin 1 Antikörper (C-Term)

Produktnummer ABIN3043211

Produktdetails anti-beta Defensin 1 Antikörper

Target: beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

Bindungsspezifität: AA 52-68, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser beta Defensin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: Anti-beta Defensin 1/DEFB1 Antibody Picoband®

Sequenz: FTKIQGTCYR GKAKCCK

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-beta Defensin 1/DEFB1 Antibody (ABIN3043211). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human beta Defensin 1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Jia, H. P., Starner, T., Ackermann, M., Kirby, P., Tack, B. F., McCray, P. B., Jr.Abundant human beta-defensin-1 expression in milk and mammary gland epithelium.J. 2. Liu, L., Zhao, C., Heng, H. H. Q., Ganz, T.The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry. 3. Valore, E. V., Park, C. H., Quayle, A. J., Wiles, K. R., McCray, P. B., Jr., Ganz, T.Human beta-defensin-1: an antimicrobial peptide of urogenital tissues.J. Clin.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu beta Defensin 1

Target: beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

Andere Bezeichnung: DEFB1 (DEFB1 Produkte)

Hintergrund:

Synonyms: Beta-defensin 1,BD-1,hBD-1,Defensin, beta 1,DEFB1,BD1, HBD1,

Tissue Specificity: Plasma.

Background: DEFB1,Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.

Sequence Similarities: Belongs to the beta-defensin family.

Molekulargewicht: 7 kDa

UniProt: P60022