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beta Defensin 1 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-beta Defensin 1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, beta Defensin 1 in Proben von Human zu detektieren.
Produktnummer ABIN3043211

Kurzübersicht für beta Defensin 1 Antikörper (C-Term) (ABIN3043211)

Target

Alle beta Defensin 1 (DEFB1) Antikörper anzeigen
beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

Reaktivität

  • 51
  • 26
  • 12
  • 11
  • 5
Human

Wirt

  • 74
  • 13
  • 2
  • 1
Kaninchen

Klonalität

  • 74
  • 16
Polyklonal

Konjugat

  • 45
  • 16
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser beta Defensin 1 Antikörper ist unkonjugiert

Applikation

  • 61
  • 40
  • 28
  • 25
  • 24
  • 13
  • 13
  • 7
  • 5
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 17
    • 9
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 52-68, C-Term

    Verwendungszweck

    Anti-beta Defensin 1/DEFB1 Antibody Picoband®

    Sequenz

    FTKIQGTCYR GKAKCCK

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-beta Defensin 1/DEFB1 Antibody (ABIN3043211). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human beta Defensin 1.

    Isotyp

    IgG
  • Applikationshinweise

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. Jia, H. P., Starner, T., Ackermann, M., Kirby, P., Tack, B. F., McCray, P. B., Jr.Abundant human beta-defensin-1 expression in milk and mammary gland epithelium.J. 2. Liu, L., Zhao, C., Heng, H. H. Q., Ganz, T.The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry. 3. Valore, E. V., Park, C. H., Quayle, A. J., Wiles, K. R., McCray, P. B., Jr., Ganz, T.Human beta-defensin-1: an antimicrobial peptide of urogenital tissues.J. Clin.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))

    Andere Bezeichnung

    DEFB1

    Hintergrund

    Synonyms: Beta-defensin 1,BD-1,hBD-1,Defensin, beta 1,DEFB1,BD1, HBD1,

    Tissue Specificity: Plasma.

    Background: DEFB1,Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.

    Sequence Similarities: Belongs to the beta-defensin family.

    Molekulargewicht

    7 kDa

    UniProt

    P60022
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