beta Defensin 1 Antikörper (C-Term)
Kurzübersicht für beta Defensin 1 Antikörper (C-Term) (ABIN3043211)
Target
Alle beta Defensin 1 (DEFB1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 52-68, C-Term
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Verwendungszweck
- Anti-beta Defensin 1/DEFB1 Antibody Picoband®
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Sequenz
- FTKIQGTCYR GKAKCCK
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Produktmerkmale
- Anti-beta Defensin 1/DEFB1 Antibody (ABIN3043211). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human beta Defensin 1.
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Isotyp
- IgG
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Applikationshinweise
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Jia, H. P., Starner, T., Ackermann, M., Kirby, P., Tack, B. F., McCray, P. B., Jr.Abundant human beta-defensin-1 expression in milk and mammary gland epithelium.J. 2. Liu, L., Zhao, C., Heng, H. H. Q., Ganz, T.The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry. 3. Valore, E. V., Park, C. H., Quayle, A. J., Wiles, K. R., McCray, P. B., Jr., Ganz, T.Human beta-defensin-1: an antimicrobial peptide of urogenital tissues.J. Clin. -
Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Haltbarkeit
- 12 months
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- beta Defensin 1 (DEFB1) (Defensin, beta 1 (DEFB1))
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Andere Bezeichnung
- DEFB1
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Hintergrund
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Synonyms: Beta-defensin 1,BD-1,hBD-1,Defensin, beta 1,DEFB1,BD1, HBD1,
Tissue Specificity: Plasma.
Background: DEFB1,Beta-defensin 1, is a protein that in humans is encoded by the DEFB1 gene. DEFB1 belongs to the defensin family. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. The DEFB1 gene spans more than 7 kb and includes a large 6,962-bp intron. By 2-color fluorescence in situ hybridization on both metaphase chromosomes and released chromatin fiber, the DEFB1gene is mapped to 8p23.2-p23.1, within 100 to 150 kb of the gene for human neutrophil defensin-alpha-1. DEFB1may augment neonatal host defenses through antimicrobial effects or prime the adaptive immune system at mucosal surfaces.
Sequence Similarities: Belongs to the beta-defensin family.
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Molekulargewicht
- 7 kDa
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UniProt
- P60022
Target
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