CCL26 Antikörper (C-Term)

Produktnummer ABIN3043210

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CCL26 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CCL26 Antikörper (C-Term) (ABIN3043210)

Target: CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL26 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CCL26 Antikörper

Bindungsspezifität: AA 73-94, C-Term

Verwendungszweck: Anti-Eotaxin 3/CCL26 Antibody Picoband®

Sequenz: CTHPRKKWVQ KYISLLKTPK QL

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Eotaxin 3/CCL26 Antibody (ABIN3043210). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Eotaxin 3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human
1. Guo, R.-F., Ward, P. A., Hu, S.-M., McDuffie, J. E., Huber-Lang, M., Shi, M. M.Molecular cloning and characterization of a novel human CC chemokine, SCYA26.Genomics 58: 313-317, 1999. 2. Kitaura, M., Suzuki, N., Imai, T., Takagi, S., Suzuki, R., Nakajima, T., Hirai, K., Nomiyama, H., Yoshie, O.Molecular cloning of a novel human CC chemokine (eotaxin-3) that is a functional ligand of CC chemokine receptor 3.J. Biol. Chem. 274: 27975-27980, 1999. 3. Nakayama, T., Watanabe, Y., Oiso, N., Higuchi, T., Shigeta, A., Mizuguchi, N., Katou, F., Hashimoto, K., Kawada, A., Yoshie, O.Eotaxin-3/CC chemokine ligand 26 is a functional ligand for CX3CR1.J. Immun. 185: 6472-6479, 2010.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CCL26

Target: CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))

Andere Bezeichnung: CCL26

Hintergrund:

Synonyms: C-C motif chemokine 26,CC chemokine IMAC,Eotaxin-3,Macrophage inflammatory protein 4-alpha,MIP-4-alpha,Small-inducible cytokine A26,Thymic stroma chemokine-1,TSC-1,CCL26,SCYA26,UNQ216/PRO242,

Tissue Specificity: Ubiquitously expressed at low levels in various tissues including heart and ovary.

Background: Eotaxin-3 is a small cytokine belonging to the CC chemokine family that is also called CCL26, Chemokine (C-C motif) ligand 26. Chemokines play pivotal roles in health and disease by controlling migration and tissue localization of specific types of cells expressing their cognate receptors. Eotaxin-3 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3. It is expressed by several tissues including heart, lung and ovary, and in endothelial cells that have been stimulated with the cytokine interleukin 4. This gene for chemokine is located on human chromosome 7. Eotaxin-3 induced migration of eosinophils and basophils only at a 10-fold higher concentration than eotaxin.

Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

Molekulargewicht: 11 kDa

UniProt: Q9Y258

Pathways: Regulation of Actin Filament Polymerization