CXCL16 Antikörper (Middle Region)

Produktnummer ABIN3043204

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CXCL16 in WB und IHC. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für CXCL16 Antikörper (Middle Region) (ABIN3043204)

Target: CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCL16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CXCL16 Antikörper

Bindungsspezifität: AA 103-116, Middle Region

Verwendungszweck: Anti-C-X-C motif chemokine 16 CXCL16 Antibody Picoband®

Sequenz: HGKSFHHQKH LPQA

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-C-X-C motif chemokine 16 CXCL16 Antibody (ABIN3043204). Tested in IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse CXCL16.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse
Western blot, 0.1-0.5 μg/mL, Mouse
1. Matloubian, M., David, A., Engel, S., Ryan, J. E., Cyster, J. G.A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo.Nature Immun. 1: 298-304, 2000. 2. Shimaoka, T., Kume, N., Minami, M., Hayashida, K., Kataoka, H., Kita, T., Yonehara, S.Molecular cloning of a novel scavenger receptor for oxidized low absorbance lipoprotein, SR-PSOX, on macrophages.J. Biol. Chem. 275: 40663-40666, 2000. 3. Wilbanks, A., Zondlo, S. C., Murphy, K., Mak, S., Soler, D., Langdon, P., Andrew, D. P., Wu, L., Briskin, M.Expression cloning of the STRL33/BONZO/TYMSTR ligand reveals elements of CC, CXC, CX3C chemokines.J. Immun. 166: 5145-5154, 2001.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CXCL16

Target: CXCL16 (Chemokine (C-X-C Motif) Ligand 16 (CXCL16))

Andere Bezeichnung: CXCL16

Hintergrund:

Synonyms: C-X-C motif chemokine 16,Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein,SR-PSOX,Small-inducible cytokine B16,Transmembrane chemokine CXCL16,Cxcl16,Srpsox,

Tissue Specificity: Widely expressed. Not detected in purified B- and T-cells. .

Background: CXCL16, Chemokine (C-X-C motif) ligand 16, is a small cytokine belonging to the CXC chemokine family. Larger than other chemokines (with 254 amino acids ), CXCL16 is composed of a CXC chemokine domain, a mucin-like stalk, a transmembrane domain and a cytoplasmic tail containing a potential tyrosine phosphorylation site that may bind SH2. By somatic cell hybrid analysis, the CXCL16 gene is mapped to 17p13, a locus separate from all other known chemokines. Chemotaxis assays found that CXCL16 induced a strong chemotactic response in activated CD8 T cells. In addition, CXCL16 induced calcium mobilization.

Sequence Similarities: Belongs to the SFTPA family.

Molekulargewicht: 26-35 kDa