CCR4 Antikörper (Middle Region)

Produktnummer ABIN3043172

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-CCR4 Antikörper wird verwendet zum Nachweis von CCR4 in Proben von Maus und Ratte. Er wurde validiert für WB.

Kurzübersicht für CCR4 Antikörper (Middle Region) (ABIN3043172)

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CCR4 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: Anti-C-C chemokine receptor type 4 CCR4 Antibody

Sequenz: SYTQSTVDHD FRDAL

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Homologie: identical to the related rat sequence.

Produktmerkmale: Anti-C-C chemokine receptor type 4 CCR4 Antibody. Tested in WB applications. This antibody reacts with Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse CCR4, identical to the related rat sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Mouse, Rat

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CCR4 Antikörper (ABIN3043172)

Zhao, Bu, Wang, Ma, Ma: "GEC-derived SFRP5 inhibits Wnt5a-induced macrophage chemotaxis and activation." in: PLoS ONE, Vol. 9, Issue 1, pp. e85058, (2014) (PubMed).

Details zu CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Andere Bezeichnung: CCR4

Hintergrund:

Background: CCR4,C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene. CCR4 has also recently been designated CD194 (cluster of differentiation 194). The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines. The CCR4 gene is mapped to chromosome 3. Chemokines are a group of small structurally related proteins that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.

Gene Full Name: C-C motif chemokine receptor 4

Sequence Similarities: Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Molekulargewicht: 41 kDa

Gen-ID: 12773

UniProt: P51680