CYGB Antikörper (N-Term)

Produktnummer ABIN3043127

Der Kaninchen Polyklonal Anti-CYGB-Antikörper wurde für WB validiert. Er ist geeignet, CYGB in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für CYGB Antikörper (N-Term) (ABIN3043127)

Target: CYGB (Cytoglobin (CYGB))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYGB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CYGB Antikörper

Bindungsspezifität: AA 50-68, N-Term

Verwendungszweck: Anti-Cytoglobin/CYGB Antibody Picoband®

Sequenz: FVNFPSAKQY FSQFKHMED

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Cytoglobin/CYGB Antibody (ABIN3043127). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Cytoglobin, identical to the related rat sequence, different from the related mouse sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Asahina, K., Kawada, N., Kristensen, D. B., Nakatani, K., Seki, S., Shiokawa, M., Tateno, C., Obara, M., Yoshizato, K. Characterization of human stellate cell activation-associated protein and its expression in human liver. Biochim. Biophys. Acta 1577: 471-475, 2002. 2. Burmester, T., Ebner, B., Weich, B., Hankeln, T. Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues. Molec. Biol. Evol. 19: 416-421, 2002. 3. Geuens, E., Brouns, I., Flamez, D., Dewilde, S., Timmermans, J.-P., Moens, L. A globin in the nucleus! J. Biol. Chem. 278: 30417-30420, 2003.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CYGB

Target: CYGB (Cytoglobin (CYGB))

Andere Bezeichnung: CYGB

Hintergrund:

Synonyms: Cytoglobin,Histoglobin,HGb,Stellate cell activation-associated protein,CYGB,STAP,

Tissue Specificity: Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine. .

Background: Cytoglobin (CYGB), also called HGB or STAP, is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues, scavenge nitric oxide or other reactive oxygen species, or serve a protective function during oxidative stress. The cytoglobin gene is mapped on 17q25.1. The CYGB gene contains 4 exons and spans about 9 kb. Cytoglobin has many elements common to vertebrate globins, including invariant histidine residues, and the amino acids that form the heme pocket share similarity with pentacoordinate myoglobin. In contrast to the high oxygen affinities displayed by most hexacoordinate hemoglobins, the characteristics of CYGB indicate that it can facilitate oxygen transport. Because the oxygen affinity of CYGB is more similar to myoglobin than to neuroglobin, and the oxy form of CYGB resists autooxidation, CYGB is proposed to represent a tissue oxygen reservoir by Sawai et al.

Sequence Similarities: Belongs to the APP family.

Molekulargewicht: 21 kDa