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Lipocalin 1 Antikörper (Middle Region)

Dieses Anti-Lipocalin 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Lipocalin 1 in WB und IHC. Geeignet für Human.
Produktnummer ABIN3043125

Kurzübersicht für Lipocalin 1 Antikörper (Middle Region) (ABIN3043125)

Target

Alle Lipocalin 1 (LCN1) Antikörper anzeigen
Lipocalin 1 (LCN1)

Reaktivität

  • 35
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 31
  • 8
  • 1
Kaninchen

Klonalität

  • 32
  • 7
  • 1
Polyklonal

Konjugat

  • 26
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Lipocalin 1 Antikörper ist unkonjugiert

Applikation

  • 38
  • 13
  • 13
  • 11
  • 11
  • 8
  • 7
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 110-124, Middle Region

    Verwendungszweck

    Anti-Lipocalin-1 LCN1 Antibody Picoband®

    Sequenz

    HVKDHYIFYC EGELH

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Lipocalin-1 LCN1 Antibody (ABIN3043125). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence in the middle region of human LCN1.

    Isotyp

    IgG
  • Applikationshinweise

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. Baumgartner, M., Holzfeind, P., Redl, B. Assignment of the gene for human tear prealbumin (LCN1), a member of the lipocalin superfamily, to chromosome 8q24. Cytogenet. Cell Genet. 65: 101-103, 1994. 2. Blaker, M., Kock, K., Ahlers, C., Buck, F., Schmale, H. Molecular cloning of human von Ebner's gland protein, a member of the lipocalin superfamily highly expressed in lingual salivary glands. Biochim. Biophys. Acta 1172: 131-137, 1993. 3. Glasgow BJ, Abduragimov AR, Gasymov OK, Yusifov TN (2003). "Tear lipocalin: structure, function and molecular mechanisms of action". Adv. Exp. Med. Biol. 506 (Pt A): 555-65.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    Lipocalin 1 (LCN1)

    Andere Bezeichnung

    LCN1

    Hintergrund

    Synonyms: Lipocalin-1,Tear lipocalin,Tlc,Tear prealbumin,TP,Von Ebner gland protein,VEG protein,LCN1,VEGP,

    Tissue Specificity: Mainly expressed in lachrymal and salivary glands. Also expressed in the prostate.

    Background: Lipocalin-1 (LCN1), also known as PREALBUMIN, TEAR or VEGP, is a protein that in humans is encoded by the LCN1 gene. Lipocalin-1 is a member of the lipocalin family of small secretory proteins, which is mapped on 9q34.3. Lipocalin-1 is the primary lipid binding protein in tears and is overproduced in response to multiple stimuli including infection and stress. It may be a marker for chromosome aneuploidy as well as an autoantigen in Sjogren's syndrome. LCN1 inhibits the cysteine-protease papain in vitro, similar to cystatins. And LCN1 plays a role in the nonimmunologic defense and in the control of inflammatory processes in oral and ocular tissues. The investigations presented the first clear evidence that LCN1 is induced in infection or inflammation and supported the idea that this lipocalin functions as a physiologic protection factor of epithelia in vivo.

    Molekulargewicht

    19 kDa

    UniProt

    P31025
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