NLRP4G Antikörper (C-Term)
Kurzübersicht für NLRP4G Antikörper (C-Term) (ABIN3043104)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- Anti-NLRP4G Antibody
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Sequenz
- SLQYLDLGCS FLTHSEVK
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Spezifität
- No cross reactivity with other proteins.
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Produktmerkmale
- Anti-NLRP4G Antibody. Tested in IHC, WB applications. This antibody reacts with Mouse.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse NLRP4G.
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Isotyp
- IgG
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Applikationshinweise
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, MouseWestern blot, 0.1-0.5 μg/mL, Mouse
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Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Haltbarkeit
- 12 months
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: "Nlrp4g is an oocyte-specific gene but is not required for oocyte maturation in the mouse." in: Reproduction, fertility, and development, Vol. 26, Issue 5, pp. 758-68, (2014) (PubMed).
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- NLRP4G (NLR Family, Pyrin Domain Containing 4G (NLRP4G))
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Andere Bezeichnung
- Nlrp4g
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Hintergrund
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Background: Stra8, stimulated by retinoic acid 8, is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons. And this gene is mapped to chromosome 7q31. Retinoic acid (RA) signaling was required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce Stra8 expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying Stra8 expression in embryonic testis. Since RA signaling regulated Stra8 expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.
Gene Full Name: NLR family, pyrin domain containing 4G
Sequence Similarities: Contains DAPIN domain.
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Molekulargewicht
- 55 kDa
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Gen-ID
- 235779
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UniProt
- Q66JP4
Target
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