CHRNA1 Antikörper (N-Term)

Produktnummer ABIN3043100

Produktdetails anti-CHRNA1 Antikörper

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Bindungsspezifität: AA 22-36, N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Acetylcholine receptor subunit alpha(CHRNA1) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: EHETRLVAKL FKDYS

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Acetylcholine receptor subunit alpha(CHRNA1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: cholinergic receptor, nicotinic, alpha 1(muscle)
Protein Name: Acetylcholine receptor subunit alpha

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Nicotinic Acetylcholine Receptor alpha 1(22-36aa EHETRLVAKLFKDYS), identical to the related rat sequence, different from the related mouse sequence by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu CHRNA1

Target: CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))

Andere Bezeichnung: CHRNA1 (CHRNA1 Produkte)

Synonyme: CHRNA1 antikoerper, ACHRA antikoerper, ACHRD antikoerper, CHRNA antikoerper, CMS2A antikoerper, FCCMS antikoerper, SCCMS antikoerper, NACHRA1 antikoerper, AI385656 antikoerper, AI608266 antikoerper, Achr-1 antikoerper, Acra antikoerper, cholinergic receptor nicotinic alpha 1 subunit antikoerper, cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) antikoerper, CHRNA1 antikoerper, Chrna1 antikoerper

Hintergrund: CHRNA, also termed ACHRA, is mapped on 2q24-q32.This gene encodes the alpha subunit of the muscle acetylcholine receptor, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis. The protein-coding sequence of the human alpha subu gene is divided into 9 exons that correspond to different structural and functional domains of the precursor molecule.

Synonyms: Acetylcholine receptor subunit alpha antibody|ACHA_HUMAN antibody|ACHRA antibody|ACHRD antibody|CHNRA antibody|Cholinergic receptor nicotinic alpha polypeptide 1 antibody|Cholinergic receptor, nicotinic, alpha polypeptide 1(muscle) antibody|CHRNA antibody|Chrna1 antibody|CMS2A antibody|FCCMS antibody|Nicotinic cholinergic receptor alpha 1 antibody|SCCMS antibody|Schizophrenia neurophysiologic defect candidate antibody

UniProt: P02708

Pathways: Skeletal Muscle Fiber Development