CHRNA1 Antikörper (N-Term)
Kurzübersicht für CHRNA1 Antikörper (N-Term) (ABIN3043100)
Target
Alle CHRNA1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 22-36, N-Term
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Verwendungszweck
- Anti-Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody
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Sequenz
- EHETRLVAKL FKDYS
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins
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Produktmerkmale
- Anti-Nicotinic Acetylcholine Receptor alpha 1/CHRNA1 Antibody (ABIN3043100). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human Nicotinic Acetylcholine Receptor alpha 1, identical to the related rat sequence, different from the related mouse sequence by one amino acid.
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Isotyp
- IgG
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Applikationshinweise
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
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Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CHRNA1 (Acetylcholine Receptor Subunit alpha (CHRNA1))
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Andere Bezeichnung
- CHRNA1
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Hintergrund
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Synonyms: Acetylcholine receptor subunit alpha,CHRNA1,ACHRA, CHNRA,
Tissue Specificity: Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus.
Background: CHRNA, also termed ACHRA, is mapped on 2q24-q32.This gene encodes the alpha subunit of the muscle acetylcholine receptor, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis. The protein-coding sequence of the human alpha subu gene is divided into 9 exons that correspond to different structural and functional domains of the precursor molecule.
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Molekulargewicht
- 69 kDa
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UniProt
- P02708
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Pathways
- Skeletal Muscle Fiber Development
Target
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