SSTR1 Antikörper (C-Term)

Produktnummer ABIN3043098

Produktdetails anti-SSTR1 Antikörper

Target: SSTR1 (Somatostatin Receptor 1 (SSTR1))

Bindungsspezifität: AA 361-381, C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SSTR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: Anti-Somatostatin Receptor 1/SSTR1 Antibody Picoband®

Sequenz: RAYSVEDFQP ENLESGGVFR N

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Somatostatin Receptor 1/SSTR1 Antibody (ABIN3043098). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Somatostatin Receptor 1, identical to the related rat and mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human, Mouse
Western blot, 0.1-0.5 μg/mL, Rat, Human, Mouse
1. Kubota, A., Yamada, Y., Kagimoto, S., Shimatsu, A., Imamura, M., Tsuda, K., Imura, H., Seino, S., Seino, Y.Identification of somatostatin receptor subtypes and an implication for the efficacy of somatostatin analogue SMS 201-995 in treatment of human endocrine tumors.J. Clin. Invest. 93: 1321-1325, 1994. 2. Yamada, Y., Post, S. R., Wang, K., Tager, H. S., Bell, G. I., Seino, S.Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney.Proc. Nat. Acad. Sci. 89: 251-255, 1992.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-SSTR1 Antikörper (ABIN3043098)

Guo, Shi, Zhou, Chen: "Somatostatin receptors 3, 4 and 5 play important roles in gallbladder cancer." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 7, pp. 4071-5, (2013) (PubMed).

Details zu SSTR1

Target: SSTR1 (Somatostatin Receptor 1 (SSTR1))

Andere Bezeichnung: SSTR1 (SSTR1 Produkte)

Hintergrund:

Synonyms: Somatostatin receptor type 1,SS-1-R,SS1-R,SS1R,SRIF-2,SSTR1,

Tissue Specificity: Fetal kidney, fetal liver, and adult pancreas, brain, lung, jejunum and stomach.

Background: SSTR1 (Somatostatin receptor type 1) is a protein that in humans is encoded by the SSTR1 gene. The SSTR1 gene is mapped to chromosome 14. Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. The encoded protein is a member of the superfamily of somatostatin receptors having seven transmembrane segments, and is expressed in highest levels in jejunum and stomach.

Sequence Similarities: Belongs to the transcription factor STAT family.

Molekulargewicht: 60 kDa

UniProt: P30872