SPTLC1 Antikörper (Middle Region)

Produktnummer ABIN3043056

Produktdetails anti-SPTLC1 Antikörper

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Bindungsspezifität: AA 138-154, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPTLC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Serine palmitoyltransferase 1(SPTLC1) detection. Tested with WB, IHC-P in Human.

Sequenz: FYGTFDVHLD LEDRLAK

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Serine palmitoyltransferase 1(SPTLC1) detection. Tested with WB, IHC-P in Human.
Gene Name: serine palmitoyltransferase, long chain base subunit 1
Protein Name: Serine palmitoyltransferase 1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human SPTLC1(138-154aa FYGTFDVHLDLEDRLAK).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SPTLC1

Target: SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))

Andere Bezeichnung: SPTLC1 (SPTLC1 Produkte)

Synonyme: ATSPT1 antikoerper, SERINE PALMITOYLTRANSFERASE 1 antikoerper, serine palmitoyltransferase 1 antikoerper, Afu6g00300 antikoerper, HSAN1 antikoerper, HSN1 antikoerper, LBC1 antikoerper, LCB1 antikoerper, SPT1 antikoerper, SPTI antikoerper, wu:fc75h04 antikoerper, wu:fp41c08 antikoerper, zgc:112247 antikoerper, AW552086 antikoerper, C77762 antikoerper, E030036H05 antikoerper, Lcb1 antikoerper, RGD1306617 antikoerper, Spt1 antikoerper, serine palmitoyltransferase 1 antikoerper, Serine palmitoyltransferase 1 antikoerper, serine palmitoyltransferase long chain base subunit 1 antikoerper, serine palmitoyltransferase, long chain base subunit 1 antikoerper, serine palmitoyltransferase, long chain base subunit 1 L homeolog antikoerper, SPT1 antikoerper, AFUA_6G00300 antikoerper, PAS_FragB_0040 antikoerper, SPTLC1 antikoerper, sptlc1 antikoerper, sptlc1.L antikoerper, Sptlc1 antikoerper

Hintergrund: SPTLC1(Serine palmitoyltransferase, long chain base subunit 1), also known as SPT1, LCB1, is a protein which in humans is encoded by the SPTLC1 gene. Dawkins et al.(2001)noted that the SPTLC1 gene maps to chromosome 9q22.1-q22.3. Serine palmitoyltransferase, which consists of two different subunits, is the initial enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified.

Synonyms: HSAN antibody|HSAN1 antibody|HSN1 antibody|LBC1 antibody|LCB 1 antibody|LCB1 antibody|Long chain base biosynthesis protein 1 antibody|MGC14645 antibody|Serine C palmitoyltransferase antibody|Serine palmitoyl CoA transferase 1 antibody|Serine palmitoyltransferase 1 antibody|Serine palmitoyltransferase long chain base subunit 1 antibody|Serine palmitoyltransferase subunit 1 antibody|Serine-palmitoyl-CoA transferase 1 antibody|SPT 1 antibody|SPT1 antibody|SPTC1_HUMAN antibody|SPTI antibody|SPTLC 1 antibody|SPTLC1 antibody

UniProt: O15269