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SSX2 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-SSX2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, SSX2 in Proben von Human zu detektieren.
Produktnummer ABIN3043034

Kurzübersicht für SSX2 Antikörper (C-Term) (ABIN3043034)

Target

Alle SSX2 Antikörper anzeigen
SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

Reaktivität

  • 49
  • 3
  • 2
Human

Wirt

  • 43
  • 6
Kaninchen

Klonalität

  • 46
  • 3
Polyklonal

Konjugat

  • 21
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SSX2 Antikörper ist unkonjugiert

Applikation

  • 34
  • 13
  • 13
  • 10
  • 5
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 157-184, C-Term

    Verwendungszweck

    Anti-Protein SSX2 SSX2 Antibody Picoband®

    Sequenz

    NREAQEKEER RGTAHRWSSQ NTHNIGRF

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-Protein SSX2 SSX2 Antibody (ABIN3043034). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human Protein SSX2.

    Isotyp

    IgG
  • Applikationshinweise

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. Crew, A. J., Clark, J., Fisher, C., Gill, S., Grimer, R., Chand, A., Shipley, J., Gusterson, B. A., Cooper, C. S. : Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma. EMBO J. 14: 2333-2340, 1995.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Konservierungsmittel

    Thimerosal (Merthiolate), Sodium azide

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))

    Andere Bezeichnung

    Protein SSX2

    Hintergrund

    Synonyms: Protein SSX2,Cancer/testis antigen 5.2,CT5.2,Synovial sarcoma, X breakpoint 2,Tumor antigen HOM-MEL-40,SSX2,SSX2A,SSX2B,

    Tissue Specificity: Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.

    Background: Synovial sarcoma, X breakpoint 2, also known as SSX2, is a human gene. The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. SSX1, SSX2 and SSX4 genes have been involved in the t (X,18) translocation characteristically found in all synovial sarcomas. The SSX1 and SSX2 genes encode closely related proteins (81 % identity) of 188 amino acids that are rich in charged amino acids. The N-terminal portion of each SSX protein exhibits homology to the Kruppel-associated box (KRAB), a transcriptional repressor domain previously found only in Kruppel-type zinc finger proteins.

    Sequence Similarities: Belongs to the SSX family.

    Molekulargewicht

    104 kDa

    UniProt

    Q16385
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