NOXA1 Antikörper (Middle Region)

Produktnummer ABIN3042993

Produktdetails anti-NOXA1 Antikörper

Target: NOXA1 (NADPH Oxidase Activator 1 (NOXA1))

Bindungsspezifität: AA 176-195, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NOXA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for NADPH oxidase activator 1(NOXA1) detection. Tested with WB in Human.

Sequenz: RQVPRGEVFR PHRWHLKHLE

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for NADPH oxidase activator 1(NOXA1) detection. Tested with WB in Human.
Gene Name: NADPH oxidase activator 1
Protein Name: NADPH oxidase activator 1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human NOXA1(176-195aa RQVPRGEVFRPHRWHLKHLE).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu NOXA1

Target: NOXA1 (NADPH Oxidase Activator 1 (NOXA1))

Andere Bezeichnung: NOXA1 (NOXA1 Produkte)

Hintergrund: NOXA1(NADPH oxidase activator 1), also called NOX ACTIVATOR 1 or p51-NOX, is an enzyme that in humans is encoded by the NOXA1 gene. Hartz(2007) mapped the NOXA1 gene to chromosome 9q34.3 based on an alignment of the NOXA1 sequence with the genomic sequence(build 36.1). Banfi et al.(2003) mapped the mouse Noxa1 gene to chromosome 2. Using yeast 2-hybrid assays, Takeya et al.(2003) showed that human p51-NOX interacted with constitutively active forms of RAC1 and RAC2. In vitro binding assays revealed that p51-NOX bound GTP-bound RAC1, but not GDP-bound RAC1. p51-NOX also bound p47-PHOX(NCF1) and p41-NOX(NOXO1), and trp436 within the SH3 domain of p51-NOX was required for these interactions. Human cell lines or COS-7 cells cotransfected with p51-NOX and p41-NOX and either gp91-PHOX(CYBB) or NOX1 produced superoxide. Cells individually transfected with NOX1, p41-NOX, or p51-NOX and cells transfected with only p41-NOX and p51-NOX showed no superoxide production.

Synonyms: Antigen NY CO 31 antibody|Antigen NY-CO-31 antibody|FLJ25475 antibody|Inhibitory NADPH oxidase activator 1 antibody|MGC131800 antibody|NADPH oxidase activator 1 antibody|NCF2 like protein antibody|NCF2-like protein antibody|NOX activator 1 antibody|NOXA 1 antibody|Noxa1 antibody|NOXA1_HUMAN antibody|NY CO 31 antibody|p51 nox antibody|p51-nox antibody|p51NOX antibody|P67phox like factor antibody|P67phox-like factor antibody|SDCCAG31 antibody|Serologically defined colon cancer antigen 31 antibody