CETP Antikörper (C-Term)

Produktnummer ABIN3042949

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CETP in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CETP Antikörper (C-Term) (ABIN3042949)

Target: CETP (Cholesteryl Ester Transfer Protein (CETP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CETP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CETP Antikörper

Bindungsspezifität: AA 368-382, C-Term

Verwendungszweck: Anti-CETP Antibody Picoband®

Sequenz: PRPDQQHSVA YTFEE

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-CETP Antibody (ABIN3042949). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CETP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Human
1. Day, J. R., Albers, J. J., Lofton-Day, C. E., Gilbert, T. L., Ching, A. F. T., Grant, F. J., O'Hara, P. J., Marcovina, S. M., Adolphson, J. L. Complete cDNA encoding human phospholipid transfer protein from human endothelial cells. J. Biol. Chem. 269: 9388-9391, 1994. 2. Okamoto, H., Yonemori, F., Wakitani, K., Minowa, T., Maeda, K., Shinkai, H. A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits. Nature 406: 203-207, 2000. 3. Sparkes, R. S., Drayna, D., Mohandas, T., Klisak, I., Heinzmann, C., Lawn, R., Lusis, A. J. Assignment of cholesterol ester transfer protein (CETP) gene to human 16q21. (Abstract) Cytogenet. Cell Genet. 46: 696 only, 1987.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CETP

Target: CETP (Cholesteryl Ester Transfer Protein (CETP))

Andere Bezeichnung: CETP

Hintergrund:

Synonyms: Cholesteryl ester transfer protein ,Lipid transfer protein I ,CETP ,

Tissue Specificity: Expressed by the liver and secreted in plasma.

Background: CETP (Cholesteryl Ester Transfer Protein Plasma), is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. CETP is also known as lipid transfer protein I (Day et al., 1994). Sparkes et al. (1987) used a CETP probe against DNA from a human/mouse somatic cell hybrid panel to assign the CETP gene to chromosome 16. Because the role of CETP in atherosclerosis remained unclear, Okamoto et al. (2000) attempted to develop a potent, specific CETP inhibitor. One inhibitor, JTT-705, forms a disulfide bond with CETP and increases high density lipoprotein (HDL) cholesterol, decreases non-HDL cholesterol, and inhibits the progression of atherosclerosis in rabbits.

Sequence Similarities: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

Molekulargewicht: 22 kDa

UniProt: P11597